Code No. |
M062-3 |
Anti-SOD1 (Human) mAb
|
Price |
¥52,800
|
Size |
100 µL (1 mg/mL) |
Availability (in Japan) |
1-9
(In Japan at 00:05, Apr 24, 2024 in JST)
|
Clonality |
Monoclonal |
Clone |
1G2 |
Isotype
(Immunized Animal) |
Mouse IgG1 κ |
Applications |
WB 1 µg/mL IH* reported. (PMID: 27264390 / 28057013)
|
Immunogen
(Antigen) |
Recombinant full-length human SOD1 |
Reactivity [Gene ID] |
Human[6647], Mouse(-), Rat(-) |
Storage buffer |
1 mg/mL in PBS/50% glycerol, pH 7.2 |
Storage temp. |
-20°C |
Conjugate |
Unlabeled |
Manufacturer |
MBL |
Alternative names |
superoxide dismutase 1 |
Related products |
M200-3 Anti-NRF2 mAb
|
Product category |
Research area:Neuroscience Cellular stress |
Data |
|
Citations |
Western Blotting - Hashimoto Y et al. A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta. PNAS 98, 6336-41 (2001)(PMID:11371646)
- Hashimoto Y et al. The Gtx homeodomain transcription factor exerts neuroprotection using its homeodomain. J. Biol. Chem. 279, 16767-77 (2004)(PMID:14754886)
- Kanekura K et al. Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants. J Biol Chem. 279, 19247-56 (2004)(PMID:14970233)
- Schonhoff CM et al. S-nitrosothiol depletion in amyotrophic lateral sclerosis. PNAS 103, 2404-9 (2006)(PMID:16461917)
- Nawa M et al. A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB. Cell Signal. 20, 493-505 (2008)(PMID:18160256)
- Doi K et al. Mitochondrial changes in motor neurons of homozygotes of leucine 126 TT deletion SOD1 transgenic mice. Neuropathology 28, 269-76 (2008)(PMID:18179411)
- Ren G et al. Cu, Zn-superoxide dismutase 1 (SOD1) is a novel target of Puromycin-sensitive aminopeptidase (PSA/NPEPPS): PSA/NPEPPS is a possible modifier of amyotrophic lateral sclerosis. Mol. Neurodegener. 6, 29 (2011)(PMID:21548977)
- Hineno A et al. Distinctive clinicopathological features of 2 large families with amyotrophic lateral sclerosis having L106V mutation in SOD1 gene. J Neurol Sci. 319, 63-74 (2012)(PMID:22647583)
Immunohistochemistry - Morisaki Y et al. Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9. Sci Rep. 6, 27354 (2016)(PMID:27264390)
- Tokuda E et al. Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis. Mol Neurodegener. 12, 2 (2017)(PMID:28057013)
- Komine O et al. Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes. Cell Death Differ. (2018) In press.(PMID:29568058)
|