Antibody detailed product information

Code No.	M041-3
Anti-PML (Human) mAb
Price	¥52,800
Size	100 µL (1 mg/mL)
Availability (in Japan)	10 or more （In Japan at 00:05, Apr 17, 2024 in JST）
Clonality	Monoclonal
Clone	1B9
Isotype (Immunized Animal)	Mouse IgG1
Applications	WB　10 µg/mL IP*　reported. （PMID: 15331439） FCM　10 µg/mL IC　1 µg/mL
Immunogen (Antigen)	Recombinant Human full length PML
Reactivity [Gene ID]	Human[5371]
Storage buffer	1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp.	-20°C
Conjugate	Unlabeled
Manufacturer	MBL
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Product category	Research area:RNA-RNP Network Epigenetics Cancer
Data
Citations	Yung TM et al. Cellular dynamics of the negative transcription elongation factor NELF. Exp Cell Res. 315, 1693-705 (2009)(PMID:19245807) Western Blotting Qiu F et al. Knockdown of endogenous RNF4 exacerbates ischaemia-induced cardiomyocyte apoptosis in mice. J Cell Mol Med. 24, 9545-9559 (2020)(PMID:32722882) Immunoprecipitation Nguyen LA, et al., Physical and functional link of the leukemia-associated factors AML1 and PML. Blood. 105, 292-300 (2005)(PMID:15331439) Yoshida H et al. PML-retinoic acid receptor alpha inhibits PML IV enhancement of PU.1-induced C/EBPepsilon expression in myeloid differentiation. Mol Cell Biol. 27, 5819-34 (2007)(PMID:17562868) Tagata T et al. Phosphorylation of PML is essential for activation of C/EBP epsilon and PU.1 to accelerate granulocytic differentiation. Leukemia. 22, 273-80 (2008)(PMID:17989726) Immunocytochemistry Al Rashid ST, et al., Evidence for the direct binding of phosphorylated p53 to sites of DNA breaks in vivo. Cancer Res. 65, 10810-21. (2005)(PMID:16322227)

The availability is based on the information in Japan at 00:05, Apr 17, 2024 in JST.
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Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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