Antibody detailed product information

Code No.	M009-3
Anti-Amyloid Precursor Protein mAb
Price	¥52,800
Size	100 µL (1 mg/mL)
Availability (in Japan)	10 or more （In Japan at 17:00, Apr 20, 2024 in JST）
Clonality	Monoclonal
Clone	3E9
Isotype (Immunized Animal)	Mouse IgG1
Applications	WB　5-10 µg/mL FCM　reported. （PMID: 15509549 / 21741125） IH*　reported. （PMID: 29426875）
Immunogen (Antigen)	synthetic peptide, LEVPTDGNAGLLAEPQIAMFC, which corresponding to APP695 (18-38 aa)
Reactivity [Gene ID]	Human[351], Mouse[11820]
Storage buffer	1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp.	-20°C
Conjugate	Unlabeled
Manufacturer	MBL
Alternative names	amyloid beta (A4) precursor protein, APP
Related products	W072-3 Anti-CD358 (DR6) (Human) mAb
Product category	Research area:Neuroscience
Data
Citations	Western Blotting Sakai T and Hohjoh H. Gene silencing analyses against amyloid precursor protein (APP) gene family by RNA interference. Cell Biol Int. 30, 952-956 (2006)(PMID:16889988) Flow Cytometry Gylys KH et al. Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence. Am J Pathol. 165, 1809-1817 (2004)(PMID:15509549) Sokolow S et al. AD synapses contain abundant A?A monomer and multiple soluble oligomers, including a 56-kDa assembly. Neurobiol Aging. 33, 1545-1555 (2012)(PMID:21741125) Immunohistochemistry Ogawa Y et al. Elavl3 is essential for the maintenance of Purkinje neuron axons. Sci Rep. 8, 2722 (2018)(PMID:29426875)

The availability is based on the information in Japan at 17:00, Apr 20, 2024 in JST.
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Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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