Antibody detailed product information
| Code No. | K0227-4 | |
| Anti-CD8 (Mouse) mAb-FITC | ||
| Price | ¥27,500 | |
| Size | 1 mL (100 tests) | |
| Availability (in Japan) | 10 or more
（In Japan at 00:05, Nov 12, 2025 in JST） |
|
| Clonality | Monoclonal | |
| Clone | KT15 | |
| Isotype (Immunized Animal) |
Rat IgG2aλ | |
| Applications | FCM 10 µL (Ready for use.) |
|
| Immunogen (Antigen) |
T cell clone C6, H-2Kk restricted H-Y antigen specific CTL | |
| Reactivity [Gene ID] | Mouse[12525] |
|
| Storage buffer | PBS/1% BSA/0.09% NaN3 | |
| Storage temp. | 4°C | |
| Conjugate | FITC | |
| Manufacturer | MBL | |
| Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two α chains, or a heterodimer composed of one α and one β chain. Both α and β chains share significant homology to immunoglobulin variable light chains. CD8 α chains bind to class-I MHC molecules α3 domains. CD8 identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.This monoclonal antibody KT15 reacts with a non-polymorphic epitope on the mouse CD8 α chain (mouse Ly2.1 and Ly2.2 cells). | |
| Related products | M081-4 Rat IgG2a (isotype control)-FITC D341-4 Anti-CD4 (Mouse) mAb-FITC |
|
| Product category | Research area:Immunology Cell surface antigens | |
| Data |  |
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- The availability is based on the information in Japan at 00:05, Nov 12, 2025 in JST.
- The special price is shown in red color.
- Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
- Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization - For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
- For storage temparature: RT: room temparature
- Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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