Antibody detailed product information

Code No.	D328-3
Anti-IDH2-R172K (Human) mAb
Price	¥37,400
Size	100 µL (1 mg/mL)
Availability (in Japan)	10 or more （In Japan at 17:33, Apr 26, 2024 in JST）
Clonality	Monoclonal
Clone	KMab-1
Isotype (Immunized Animal)	Rat IgG2bκ
Applications	WB　1 µg/mL IC*　reported. （PMID: 29162772）
Reactivity [Gene ID]	Human[3418](PMID: 23376717), Dog*[479043](PMID: 29162772)
Storage buffer	1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp.	-20°C
Conjugate	Unlabeled
Manufacturer	MBL
Alternative names	mNADP-IDH, isocitrate dehydrogenase 2 (NADP+), mitochondrial
Related products	D309-3 Anti-IDH1 mAb D299-3 Anti-IDH1-R132H (Human) mAb D300-3 Anti-IDH1-R132S (Human) mAb D330-3 Anti-IDH2 mAb D331-3 Anti-IDH1-R132G (Human) mAb D336-3 Anti-IDH1 mAb D337-3 Anti-IDH2-R172M (Human) mAb D338-3 Anti-IDH2-R172W (Human) mAb D332-3 Anti-Mutated IDH1/2 (Human) mAb
Product category	Research area:Cancer Neuroscience
Data
Citations	Western Blotting Kaneko MK et al. Establishment of novel monoclonal antibodies KMab-1 and MMab-1 specific for IDH2 mutations Biochem Biophys Res Commun. 432, 40-5 (2013)(PMID:23376717) Kawakami S et al. Functional alteration of canine isocitrate dehydrogenase 2 (IDH2) via an R174K mutation. J Vet Med Sci. 80, 85-91 (2018) (PMID:29162772) Gao M et al. Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants. Cancer Sci. 110, 3306-3314 (2019)(PMID:31361380) Immunocytochemistry Kawakami S et al. Functional alteration of canine isocitrate dehydrogenase 2 (IDH2) via an R174K mutation. J Vet Med Sci. 80, 85-91 (2018) (PMID:29162772)

The availability is based on the information in Japan at 17:33, Apr 26, 2024 in JST.
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Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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