Antibody detailed product information

Code No. D278-3
Anti-GP2 (Glycoprotein 2) (Mouse) mAb
Price ¥52,800
Size 100 µL (1 mg/mL)
Availability (in Japan) 10 or more
（In Japan at 00:05, Apr 19, 2024 in JST）
Clonality Monoclonal
Clone 2F11-C3
Isotype
(Immunized Animal) 		Rat IgG2aκ
Applications FCM　2 µg/mL  
IC　2 µg/mL  （PMID: 24334484）
IH　2.5 µg/mL  （PMID: 29593242 / 29386479）
Immunogen
(Antigen)		 Mouse GP2-Human Fc fusion protein without transmembrane region
Reactivity [Gene ID]

Mouse[67133]
Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C
Conjugate Unlabeled
Manufacturer MBL
Alternative names glycoprotein 2 (zymogen granule membrane), AV060639, 2310037I18Rik
Related products D278-A48 Anti-GP2 (Glycoprotein 2) (Mouse) mAb-Alexa Fluor™ 488
D278-5 Anti-GP2 (Glycoprotein 2) (Mouse) mAb-PE
D278-6 Anti-GP2 (Glycoprotein 2) (Mouse) mAb-Biotin
D277-3 Anti-GP2 (Glycoprotein 2) (Human) mAb
D277-A48 Anti-GP2 (Glycoprotein 2) (Human) mAb-Alexa Fluor™ 488
D277-5 Anti-GP2 (Glycoprotein 2) (Human) mAb-PE
Product category Research area:Immunology
Data


Citations

Immunocytochemistry

  1. Hanazato M et al. Selection of an aptamer against mouse GP2 by SELEX. Cell Struct Funct. 39, 23-9 (2014)(PMID:24334484)

Immunohistochemistry

  1. Ebisawa M et al. CCR6hiCD11c(int) B cells promote M-cell differentiation in Peyer's patch. Int Immunol. 23, 261-9 (2011)(PMID:21422150)
  2. Knoop KA et al. Distinct developmental requirements for isolated lymphoid follicle formation in the small and large intestine: RANKL is essential only in the small intestine. Am J Pathol. 179, 1861-71 (2011)(PMID:21854748)
  3. Fukuda S et al. Application of a mouse ligated Peyer’s patch intestinal loop assay to evaluate bacterial uptake by M cells. J Vis Exp. 58, e3225 (2011)(PMID:22215009)
  4. McDole JR et al. Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine. Nature 483, 345-9 (2012)(PMID:22422267)
  5. de Lau W et al. Peyer's patch M cells derived from Lgr5(+) stem cells require SpiB and are induced by RankL in cultured "miniguts". Mol Cell Biol. 32, 3639-47 (2012)(PMID:22778137)
  6. Kobayashi A et al. Identification of novel genes selectively expressed in the follicle-associated epithelium from the meta-analysis of transcriptomics data from multiple mouse cell and tissue populations. DNA Res. 19, 407-22 (2012)(PMID:22991451)
  7. Sato S et al. Transcription factor Spi-B-dependent and -independent pathways for the development of Peyer's patch M cells. Mucosal Immunol. 6, 838-46 (2013)(PMID:23212199)
  8. Rios D et al. Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria. Mucosal Immunol. 9, 907-16 (2016)(PMID:26601902)
  9. Wood MB et al. TNF-α augments RANKL-dependent intestinal M cell differentiation in enteroid cultures. Am J Physiol Cell Physiol. 311, C498-507 (2016)(PMID:27413168)
  10. Nagashima K et al. Targeted deletion of RANKL in M cell inducer cells by the Col6a1-Cre driver.  Biochem Biophys Res Commun. 493, 437-443 (2016)(PMID:28882590)
  11. Yano A et al. Peyer's Patches as a Portal for DNA Delivery by Lactococcus lactis in Vivo. Biol Pharm Bull. 41, 190-197 (2018)(PMID:29386479)
  12. Sehgal A et al. The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche. Nat Commun. 9, 1272 (2018)(PMID:29593242)
  13. Kimura S et al. Sox8 is essential for M cell maturation to accelerate IgA response at the early stage after weaning in mice. 216, 831-846 (2019)(PMID:30877171)

Immunofluorescence

  1. Kimura S et al. Osteoprotegerin-dependent M Cell Self-Regulation Balances Gut Infection and Immunity. Nat Commun. 11, 234 (2020)(PMID:31932605)
  • The availability is based on the information in Japan at 00:05, Apr 19, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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