Antibody detailed product information

Code No. D271-5 プリントPrint out
Anti-CD8 (Mouse) mAb-PE
Price ¥28,000
Size 1 mL (100 tests)
Availability (in Japan) 10 or more
(In Japan at 17:30, Aug 10, 2022 in JST)
Clonality Monoclonal
Clone KT15
Isotype
(Immunized Animal)
Rat IgG2aλ
Applications FCM 10 µL (Ready for use.)  
Immunogen
(Antigen)
T cell clone C6, H-2Kk restricted H-Y antigen specific CTL
Reactivity [Gene ID]

Mouse[12525]

Storage buffer PBS/1% BSA/0.1% ProClin 150
Storage temp. 4°C
Conjugate PE
Manufacturer MBL
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two α chains, or a heterodimer composed of one α and one β chain. Both α and β chains share significant homology to immunoglobulin variable light chains. CD8 α chains binds to class-I MHC molecules α3 domains. CD8 identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. This monoclonal antibody KT15 reacts with a non-polymorphic epitope on the mouse CD8 α chain (mouse Ly2.1 and Ly2.2 cells).
Related products D341-4 Anti-CD4 (Mouse) mAb-FITC
M090-5 Rat IgG2b (isotype control)-PE
Product category Research area:Immunology Cell surface antigens
Data

  • The availability is based on the information in Japan at 17:30, Aug 10, 2022 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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