Antibody detailed product information

Code No. D219-3
Anti-Desmoglein 3 (Mouse) mAb (No Azide)
Price ¥57,200
Size 100 µL (1 mg/mL)
Availability (in Japan) 10 or more
（In Japan at 00:05, Dec 12, 2025 in JST）
Clonality Monoclonal
Clone AK23
Isotype
(Immunized Animal) 		Mouse IgG1
Applications IP*　reported.  （PMID: 12574390）
IC　1 µg/mL  
IH　1 µg/mL  
Immunogen
(Antigen)		 hybridoma was established by fusion of splenocytes from PV model mouse and P3 mouse myeloma cells
Reactivity [Gene ID]

Human[1830], Mouse[13512]
Storage buffer 1 mg/mL in PBS, pH 7.2
Storage temp. 4°C
Conjugate Unlabeled
Manufacturer MBL
Alternative names Dsg3
Background Pemphigus vulgaris (PV) is a life -threatening autoimmune blistering disease of the skin and mucous membranes. In patients of PV, IgG autoantibodies against the cell surface of keratinocytes in stratified squamous epithelia play a major pathogenic role in loss of cell-cell adhesion. The autoimmune target of PV is desmoglein 3 (Dsg3), which is a member of the cadherin family of calcium-depending, transmembrane glycoprotein.
Related products D217-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide)
D218-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide)
Product category Research area:Immunology
Data



Citations

Immunoprecipitation

  1. Tsunoda K, et al., Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3. J Immunol. 170:2170-8. 2003(PMID:12574390)

Immunohistochemistry

  1. Tsunoda K, et al., Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3. J Immunol. 170:2170-8. 2003(PMID:12574390)

Other

  1. Yazaki J et al. HaloTag-based conjugation of proteins to barcoding-oligonucleotides. Nucleic Acids Res. 48, e8 (2019)(PMID:31752022)
References
  1. Tsunoda K et al. Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3. J Immunol. 170, 2170-8 (2003)（PMID: 12574390）
  • The availability is based on the information in Japan at 00:05, Dec 12, 2025 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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