Code No. | D219-3 | |
Anti-Desmoglein 3 (Mouse) mAb (No Azide) | ||
Price | ¥57,200 | |
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 17:33, Apr 26, 2024 in JST) |
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Clonality | Monoclonal | |
Clone | AK23 | |
Isotype (Immunized Animal) |
Mouse IgG1 | |
Applications | IP* reported. (PMID: 12574390) IC 1 µg/mL IH 1 µg/mL |
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Immunogen (Antigen) |
hybridoma was established by fusion of splenocytes from PV model mouse and P3 mouse myeloma cells | |
Reactivity [Gene ID] | ||
Storage buffer | 1 mg/mL in PBS, pH 7.2 | |
Storage temp. | 4°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | Dsg3 | |
Background | Pemphigus vulgaris (PV) is a life -threatening autoimmune blistering disease of the skin and mucous membranes. In patients of PV, IgG autoantibodies against the cell surface of keratinocytes in stratified squamous epithelia play a major pathogenic role in loss of cell-cell adhesion. The autoimmune target of PV is desmoglein 3 (Dsg3), which is a member of the cadherin family of calcium-depending, transmembrane glycoprotein. | |
Related products | D217-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide) D218-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide) |
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Product category | Research area:Immunology | |
Data | ||
Citations | Immunoprecipitation
Immunohistochemistry
Other
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References |
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