Code No. | D217-3 | Print out |
Anti-Desmoglein 3 (Mouse) mAb (No Azide) | ||
Price | ¥52,000 | |
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 17:00, Mar 28, 2024 in JST) |
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Clonality | Monoclonal | |
Clone | AK9 | |
Isotype (Immunized Animal) |
Mouse IgG1 | |
Applications | IP reported. (PMID: 12574390) IC 0.01 µg/mL IH 0.01 µg/mL |
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Immunogen (Antigen) |
hybridoma was established by fusion of splenocytes from PV model mouse and P3 mouse myeloma cells | |
Reactivity [Gene ID] | Human(-), Mouse[13512] |
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Storage buffer | 1 mg/mL in PBS, pH 7.2 | |
Storage temp. | 4°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | Dsg3 | |
Background | Pemphigus vulgaris (PV) is a life -threatening autoimmune blistering disease of the skin and mucous membranes. In patients of PV, IgG autoantibodies against the cell surface of keratinocytes in stratified squamous epithelia play a major pathogenic role in loss of cell-cell adhesion. The autoimmune target of PV is desmoglein 3 (Dsg3), which is a member of the cadherin family of calcium-depending, transmembrane glycoprotein. | |
Related products | D218-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide) D219-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide) M075-3 Mouse IgG1 (isotype control) |
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Product category | Research area:Immunology | |
Data | ||
Citations | Immunoprecipitation
Immunohistochemistry
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