Antibody detailed product information

Code No. D045-6
Anti-IL-18 (Human) mAb-Biotin
Price ¥52,800
Size 50 µL (500 µg/mL)
Availability (in Japan) 10 or more
（In Japan at 17:33, Apr 26, 2024 in JST）
Clonality Monoclonal
Clone 159-12B
Isotype
(Immunized Animal) 		Rat IgG2a
Applications ELISA　dilute 1:1,000  
Immunogen
(Antigen)		 Recombinant Human IL-18
Reactivity [Gene ID]

Human[3606], Mouse(-)
Storage buffer 0.5 mg/mL in PBS/1% BSA/0.09% NaN3
Storage temp. 4°C
Conjugate Biotin
Manufacturer MBL
Alternative names interleukin 18 (interferon-gamma-inducing factor), IGIF, IL1F4, IL-1g, IL-18
Related products D045-3 Anti-IL-18 (Human) mAb
D043-3 Anti-IL-18 (Human) mAb
D044-3 Anti-IL-18 (Human) mAb
PM014 Anti-IL-18 (Human) pAb
D044-3M2 Anti-IL-18 (Human) mAb (Functional Grade)
Product category Research area:Immunology Cytokine & Growth Factors
Citations

ELISA

  1. Giavedoni LD. Simultaneous detection of multiple cytokines and chemokines from nonhuman primates using luminex technology. J Immunol Methods. 301, 89-101 (2005)(PMID:15896800)
  2. Leach ST et al. Local and systemic interleukin-18 and interleukin-18-binding protein in children with inflammatory bowel disease. Inflamm Bowel Dis.
    14, 68-74 (2008)(PMID:17879274)
  3. Bontkes HJ et al. Tumor associated antigen and interleukin-12 mRNA transfected dendritic cells enhance effector function of natural killer cells and antigen specific T-cells. Clin Immunol. 127, 375-94 (2008)(PMID:18358784)
  4. Okano M et al. Characterization of IL-18 expression and release in the pathogenesis of chronic rhinosinusitis.  Int Arch Allergy Immunol. 160, 275-86 (2013)(PMID:23075512)
  5. Thinwa J et al. Integrin-media,ted first signal for inflammasome activation in intestinal epithelial cells. J Immunol. 193, 1373-82 (2014)(PMID:24965773)
  6. Furman D et al. Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states. Nat Med. 23, 174-184 (2017)(PMID:28092664)
  7. Lagrange B et al. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11. Nat Commun. 9, 242 (2018)(PMID:29339744)
  8. Pal A et al. Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides. Sci Rep. 9, 4913 (2019)(PMID:30894604)
  9. Kameda M et al. CXCL9, CXCL10, and CXCL11; biomarkers of pulmonary inflammation associated with autoimmunity in patients with collagen vascular diseases-associated interstitial lung disease and interstitial pneumonia with autoimmune features. PLoS One. 15, e0241719 (2020) (PMID:33137121)
  • The availability is based on the information in Japan at 17:33, Apr 26, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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