Antibody detailed product information

Code No. B-NU826UC プリントPrint out
Anti-Survivin mAb
Price ¥126,700
Size 1 mL
Availability (in Japan) 0
(Contact us)
(In Japan at 17:00, Feb 18, 2020 in JST)
Clonality Monoclonal
Clone EP119
(Immunized Animal)
Rabbit IgG
Applications IH 
Storage buffer PBS/1% BSA/0.09% NaN3
Storage temp. 4°C
Conjugate Unlabeled
Background The association of survivin expression with tumor progression, but not overall patient survival, has been observed in a variety of malignancies including renal cell carcinoma, ovary carcinoma, hepatocellular carcinoma, prostate carcinoma and breast carcinoma. However, the link between a poor prognosis and nuclear expression of Survivin in tumors is controversial. A literature review of 19 publication that measured nuclear survivin in different cancer types showed the following: 9 studies concluded that nucelar survivin was associated with an unfavorable prognosis, whereas 5 showed a favorable prognosis. The authors concluded that the nuclear pool of survivin is involved in promoting cell proliferation in most (if not all) cases, whereas the cytoplasmic pool of survivin may participate in controlling cell survival but not cell proliferation.
Product category Tools:Molecular pathology tools

  • The availability is based on the information in Japan at 17:00, Feb 18, 2020 in JST.
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  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
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