Antibody detailed product information

Code No. 566-H プリントPrint out
Anti-CD117 (c-Kit) (Human) pAb
Price ¥32,000
Size 6 mL
Availability (in Japan) 10 or more
(In Japan at 00:05, Jul 3, 2022 in JST)
Clonality Polyclonal
Clone Polyclonal
Isotype
(Immunized Animal)
Rabbit IgG
Applications IC Ready for use.  
IH Ready for use.  
Immunogen
(Antigen)
Carrier protein conjugated synthetic peptide (C-terminal of c-kit gene product (K963))
Reactivity [Gene ID]

Human[3815]

Storage buffer 20 mM HEPES/1% BSA/0.135 M NaCl/0.1% NaN3
Storage temp. 4°C
Conjugate Unlabeled
Manufacturer MBL
Alternative names KIT, PBT, SCFR
Background c-Kit, also known as stem cell factor receptor, steel factor receptor or CD117 is classified as a type III receptor tyrosine kinase (RTK) belonging to the platelet-derived growth factor receptor subfamily. Binding of stem cell factor (SCF), known as c-Kit ligand to c-Kit, initiates autophosphorylation of the receptor, subsequently leading to promotes a signal transduction cascade through Ras-Raf-MAP kinase cascade, phosphatidylinositol- 3-kinase, src family kinases, and JAK/STAT pathways. The roles of c-Kit include maturation of hematopoietic and primordial germ cells precursors and melanocytes during embryonic development. In acute myeloid leukemia (AML), c-Kit has been proposed to play a functional role, and becomes target molecule for drug development.
Related products 566 Anti-CD117 (c-Kit) (Human) pAb
PM035 Normal Rabbit IgG
D348-3 Anti-Pfetin (Human) mAb
Product category Research area:Stem cell research Cell surface antigens
Tools:Molecular pathology tools
Data

  • The availability is based on the information in Japan at 00:05, Jul 3, 2022 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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