Price
¥52,800
Availability (in Japan)
10 or more
(In Japan at 00:05,
Feb 9, 2025 in JST)
Size
50 µL
Data | |||||
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Clonality | Polyclonal | Clone | Polyclonal | ||
Isotype (Immunized Animal) | Guinea pig Ig (aff.) | ||||
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Reactivity [Gene ID] | |||||
Storage buffer | TBS/50% glycerol, pH 7.5 | ||||
Storage temp. | -20°C | Conjugate | Unlabeled | Manufacturer | MBL |
Alternative names | period circadian clock 2, FASPS, FASPS1, period2 | ||||
Background | The circadian clock is a 24-hour endogenous oscillator, which cycles via transcriptional/translational feedback loops of clock genes and their products in individual cells. CLOCK and BMAL1 are positive factors in the loop, and their complex binds to E-box elements of Period (PER) and Cryptochrome (CRY) genes. In turn, this E-box-dependent transactivation is suppressed by binding of PER and CRY proteins to the CLOCK-BMAL1 complex. Gene polymorphisms of PER2 are also associated with improper cell division, cancer development, improper alcohol intake, and familial advanced sleep-phase syndrome (FASPS). | ||||
Related products | D335-3 Anti-BMAL1 mAb D334-3 Anti-CLOCK (Mouse) mAb D333-3 Anti-CLOCK (Mouse) mAb PM075 Anti-GNAT2 (Zebrafish) pAb PM079 Anti-DBP (Mouse) pAb D349-3 Anti-CLOCK mAb PM081 Anti-Cry1 (Mouse) pAb PM082 Anti-Cry2 (Mouse) pAb PM083 Anti-Per2 (Mouse) pAb PM087 Anti-Chrono (Mouse) pAb PM091 Anti-Per1 (Mouse) pAb PM092 Anti-NR1D1 (Rev-erbα) pAb PM093 Anti-NR1D2 (Rev-erbβ) pAb PM097 Anti-NFIL3 (E4BP4) pAb PM067 Normal Guinea Pig IgG CY-1173 CycLex® CaM-kinase II Assay Kit |
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