This site is for customers in Japan. Customers in other regions, please go to Global page.
HOME > Product search results > Code No. PM050 Anti-Atg5 pAb

Code No. PM050

Anti-Atg5 pAb

Price

¥38,000

Availability (in Japan)

10 or more

(In Japan at 17:00,
Nov 14, 2019 in JST)

Size

100 µL

Data
  • Western Blotting

Clonality Polyclonal Clone Polyclonal
Isotype (Immunized Animal) Rabbit Ig (aff.)
Applications
WB
1:500  
Immunogen (Antigen) synthetic peptide corresponding to C-terminus of human Atg5
Reactivity [Gene ID]

Human[9474], Mouse[11793], Rat[365601], Hamster(-)

Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names autophagy related 5, ASP, APG5, APG5L, hAPG5, APG5-LIKE
Related products 8485 Autophagy Ab Sampler Set
M153-3 Anti-Atg5 mAb
M133-3 Anti-Atg3 mAb
PM039 Anti-Atg7 (Human) pAb
PM036 Anti-LC3 pAb
M152-3 Anti-LC3 mAb
PD042 Anti-Atg9A pAb
M154-3 Anti-Atg12 (Human) mAb
PM040 Anti-Atg16L pAb
M150-3 Anti-Atg16L mAb
M151-3 Anti-Atg10 (Human) mAb
PM072 Anti-VMP1 pAb
PD017 Anti-Beclin 1 pAb
PM040MS Anti-Atg16L pAb for My select sampler set
M150-3MS Anti-Atg16L mAb for My select sampler set
Notes This antibdy detects Atg5-Atg12 complex (55 kDa).
Citations

Western Blotting

  1. Ni HM et al. Dissecting the dynamic turnover of GFP-LC3 in the autolysosome. Autophagy 7, 188-204 (2011)(PMID:21107021)
  2. Myeku N, Figueiredo-Pereira ME. Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62. J Biol Chem. 286, 22426-40 (2011)(PMID:21536669)
  3. Ni HM et al. Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity. Am J Pathol. 183, 1815-25 (2013)(PMID:24095927)
  4. Maejima Y et al. Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nat Med. 19, 1478-88 (2013)(PMID:24141421)
  5. Manley S et al. Suppression of autophagic flux by bile acids in hepatocytes. Toxicol Sci. 137, 478-90 (2014)(PMID:24189133)
  6. Liu ML et al. Tri-ortho-cresyl phosphate induces autophagy of rat spermatogonial stem cells. Reproduction 149, 163-70 (2015)(PMID:25385720)
  7. Xu D et al. Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon. Autophagy 11, 617-28 (2015)(PMID:25906440)
  8. Matsuzawa Y et al.TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy. Autophagy 11, 1052-62 (2015)(PMID:26043155)
  9. Unuma K et al. Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy. Autophagy 11, 1520-36 (2015)(PMID:26102061)
  10. Liu X et al. Involvement of oxidative stress in tri-ortho-cresyl phosphate-induced autophagy of mouse Leydig TM3 cells in vitro. Reprod Biol Endocrinol. 14, 30 (2016)(PMID:27267904)
  11. Yamashita SI et al. Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy. J Cell Biol. 215, 649-665 (2016)(PMID:27903607)
  12. Asano J et al. Intrinsic Autophagy Is Required for the Maintenance of Intestinal Stem Cells and for Irradiation-Induced Intestinal Regeneration. Cell Rep. 20, 1050-1060 (2017)(PMID:28768191)
  13. Fujiwara M et al. Decreased grip strength, muscle pain, and atrophy occur in rats following long-term exposure to excessive repetitive motion. FEBS Open Bio. 7, 1737-1749 (2016)(PMID:29123982)
  14. Li Y et al. Impaired Fasting-Induced Adaptive Lipid Droplet Biogenesis in Liver-Specific Atg5-Deficient Mouse Liver Is Mediated by Persistent Nuclear Factor-Like 2 Activation. Am J Pathol. 188, 1833-1846 (2018)(PMID:29803835)
  15. Araki K et al. Mitochondrial protein E2F3d, a distinctive E2F3 product, mediates hypoxia-induced mitophagy in cancer cells. Commun Biol. 2, 3 (2019)(PMID:30740539)
  16. Saladini S et al. Metformin Impairs Glutamine Metabolism and Autophagy in Tumour Cells. Cells. 8, pii: E49 (2019)(PMID:30646605)
Product category
Research area
Autophagy
Brands
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 17:00, Nov 14, 2019 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.