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HOME > Product search results > Code No. M147-3 Anti-Borealin (Human) mAb

Code No. M147-3

Anti-Borealin (Human) mAb

Price

¥48,000

Availability (in Japan)

10 or more

(In Japan at 00:05,
Jan 20, 2020 in JST)

Size

100 µg/100 µL

Data
  • Immunoprecipitation

Clonality Monoclonal Clone 1D11
Isotype (Immunized Animal) Mouse IgG2a
Applications
WB
1 μg/mL  
IP
1 µg/50 µL of cell extract from 1 x 106 cells  
IC
1-5 μg/mL  
Immunogen (Antigen) Recombinant Human full length Borealin
Reactivity [Gene ID]

Human[55143]

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names CDCA8, cell division cycle associated 8, BOR, DasraB, MESRGP; BOREALI
Background Borealin is a subunit of the chromosomal passenger complex (CPC), which is necessary for chromosome segregation and cytokinesis. While CPC shows a dynamic localization pattern during mitosis, Borealin and survivin, another subunit of CPC is essential to localize CPC at centromare from prophase to anaphase. It is thought that Borealin and survivin recruit aurora B, a kinase subunit of CPC, to inner centromare to allow phosphorylating appropriate substrates.
Related products CY-1174 CycLex® Aurora Family Kinase Assay/Inhibitor Screening Kit
M076-3 Mouse IgG2a (isotype control)
Citations
  1. Labarrade F et al. CRM1 and chromosomal passenger complex component survivin are essential to normal mitosis progress and to preserve keratinocytes from mitotic abnormalities.  Int J Cosmet Sci. (2016) In press.(PMID:26859314)

Immunocytochemistry

  1. Weiderhold KN et al. Dynamic Phosphorylation of NudC by Aurora B in Cytokinesis. PLoS One 11, e0153455 (2016)(PMID:27074040)
Product category
Cancer
Research area
Cancer
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  • The availability is based on the information in Japan at 00:05, Jan 20, 2020 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.