Anti-Nuf2 (Human) mAb

Price

¥52,800

Availability (in Japan)

10 or more

（In Japan at 17:00,
Apr 24, 2024 in JST）

Size

100 µL (1 mg/mL)

Clonality	Monoclonal	Clone	4H9
Isotype (Immunized Animal)	Mouse IgG2a
Applications	WB 10 µg/mL
Immunogen (Antigen)	Recombinant Human full-length Nuf2
Reactivity [Gene ID]	Human[83540]
Storage buffer	1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp.	-20°C	Conjugate	Unlabeled	Manufacturer	MBL
Alternative names	CDCA1, CT106, NUF2R
Background	Nuf2, a widely conserved protein in eukaryote, compose the Ndc80 complex with NDC80/HEC1, SPC24 and SPC25. The Ndc80 complex is a constituent of the outer plate of kinetochore and acts to establish kinetochore-spindle connection at centromere for chromosome segregation in mitosis. Nuf2 localizes to kinetochores from late prophase to anaphase.
Related products	D115-3 Anti-CENP-A (Human) mAb
Citations	Western Blotting Wu G et al. Hec1 contributes to mitotic centrosomal microtubule growth for proper spindle assembly through interaction with Hice1. Mol Cell Biol. 20, 4686-95 (2009)(PMID:19776357) Ngo B et al. Complementary interhelical interactions between three buried Glu-Lys pairs within three heptad repeats are essential for Hec1-Nuf2 heterodimerization and mitotic progression. J Biol Chem. 288, 34403-13 (2013)(PMID:24129578) Immunoprecipitation Wu G et al. Hec1 contributes to mitotic centrosomal microtubule growth for proper spindle assembly through interaction with Hice1. Mol Cell Biol. 20, 4686-95 (2009)(PMID:19776357)
Product category	Research area Cancer

The availability is based on the information in Japan at 17:00, Apr 24, 2024 in JST.
The special price is shown in red color.
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Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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