Anti-Amyloid Precursor Protein mAb

Price

¥48,000

Availability (in Japan)

10 or more

（In Japan at 00:05,
Jul 1, 2022 in JST）

Size

100 µg/100 µL

Data	Western Blotting
Clonality	Monoclonal	Clone	3E9
Isotype (Immunized Animal)	Mouse IgG1
Applications	WB 5-10 µg/mL FCM reported. （PMID: 15509549 / 21741125） IH* reported. （PMID: 29426875）
Immunogen (Antigen)	synthetic peptide, LEVPTDGNAGLLAEPQIAMFC, which corresponding to APP695 (18-38 aa)
Reactivity [Gene ID]	Human[351], Mouse[11820]
Storage buffer	1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp.	-20°C	Conjugate	Unlabeled	Manufacturer	MBL
Alternative names	amyloid beta (A4) precursor protein, APP
Related products	D029-3 Anti-Drebrin mAb W072-3 Anti-CD358 (DR6) (Human) mAb
Citations	Western Blotting Sakai T and Hohjoh H. Gene silencing analyses against amyloid precursor protein (APP) gene family by RNA interference. Cell Biol Int. 30, 952-956 (2006)(PMID:16889988) Flow Cytometry Gylys KH et al. Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence. Am J Pathol. 165, 1809-1817 (2004)(PMID:15509549) Sokolow S et al. AD synapses contain abundant A?A monomer and multiple soluble oligomers, including a 56-kDa assembly. Neurobiol Aging. 33, 1545-1555 (2012)(PMID:21741125) Immunohistochemistry Ogawa Y et al. Elavl3 is essential for the maintenance of Purkinje neuron axons. Sci Rep. 8, 2722 (2018)(PMID:29426875)
Product category	Research area Neuroscience

The availability is based on the information in Japan at 00:05, Jul 1, 2022 in JST.
The special price is shown in red color.
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Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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