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HOME > Product search results > Code No. D036-3 Anti-CD157 (BST-1) (Human) mAb

Code No.　D036-3

Anti-CD157 (BST-1) (Human) mAb

Price

¥52,800

Availability (in Japan)

10 or more

（In Japan at 00:05,
Apr 18, 2024 in JST）

Size

100 µL (1 mg/mL)

Data

  • Flow Cytometry
Clonality Monoclonal Clone RF3
Isotype (Immunized Animal) Mouse IgG1 κ
Applications
FCM
5-10 µg/mL (final concentration)  
Function*
reported.  （PMID: 21478153 / 24753259）
Immunogen (Antigen) RA-derived BM stromal cell line RASV5-5
Reactivity [Gene ID]

Human[683]
Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Background In the bone marrow (BM) hematopoietic microenvironment, stromal cells play crucial roles. Stromal cells secrete a variety of cytokines and express cell surface molecules that regulate the growth of hematopoietic cells. BM stromal cell lines derived from patients with rheumatoid arthritis (RA) have augmented ability to support the growth of a murine pre-B cell line, DW34. BST-1 (bone marrow stromal cell antigen-1) is expressed on BM stromal cell lines and is responsible for an augmented ability to support pre-B cell line growth. BST-1 is also expressed by RA-derived synovial cell lines, a myelomonocytic cell lines, and HUVEC, suggesting that BST-1 has other functional roles than just supporting pre-B cell growth.
Related products D036-4 Anti-CD157 (BST-1) (Human) mAb-FITC
D036-5 Anti-CD157 (BST-1) (Human) mAb-PE
M076-3 Mouse IgG2a (isotype control)
Citations

Flow Cytometry

  1. Ortolan E et al. Functional role and prognostic significance of CD157 in ovarian carcinoma. J Natl Cancet Inst. 102, 1160-77 (2010)(PMID:20639476)
  2. Lo Buono N et al. The CD157-integrin partnership controls transendothelial migration and adhesion of human monocytes. J Biol Chem. 286, 18681-91 (2011)(PMID:21478153)
  3. Ortolan E et al. CD157 enhances malignant pleural mesothelioma aggressiveness and predicts poor clinical outcome. Oncotarget 5, 6191-205 (2014)(PMID:25026285)

Function

  1. Lo Buono N et al. The CD157-integrin partnership controls transendothelial migration and adhesion of human monocytes. J Biol Chem. 286, 18681-91 (2011)(PMID:21478153)
  2. Morone S et al. Binding of CD157 protein to fibronectin regulates cell adhesion and spreading. J Biol Chem. 289, 15588-601 (2014)(PMID:24753259)
Product category
Research area
Immunology
Cell surface antigens
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 00:05, Apr 18, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.