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HOME > Product search results > Code No. CM004-6 Anti-SynCAM (TSLC1/CADM1) mAb-Biotin

Code No. CM004-6

Anti-SynCAM (TSLC1/CADM1) mAb-Biotin

Price

¥58,000

Availability (in Japan)

10 or more

(In Japan at 00:05,
Jan 19, 2022 in JST)

Size

100 µg/100 µL

Data
  • Flow Cytometry

Clonality Monoclonal Clone 3E1
Isotype (Immunized Animal) Chicken IgY
Applications
IP*
reported.  (PMID: 27756895
FCM
1 µg/mL  
Immunogen (Antigen) Recombinant Fc-SynCAM fusion protein
Reactivity [Gene ID]

Human[23705], Rat*[363058](PMID: 27756895)

Storage buffer 1 mg/mL in PBS/1% BSA/0.1% ProClin 150
Storage temp. 4°C Conjugate Biotin Manufacturer MBL
Alternative names cell adhesion molecule 1, IgSF4, NECL-2, SgIgSF, TSLC1, CADM1, BL2, ST17, RA175
Background SynCAM (Synaptic Cell Adhesion Molecule), also known as TSLC1 (tumor suppressor in lung cancer-1), SgIGSF, or CADM1, is a homophilic, transmembrane Ig-domain containing protein with intracellular PDZ protein-binding motifs. Although originally identified as a tumor suppressor of small lung cell carcinomas, SynCAM appears to be primarily involved in intracellular adhesion and synapse formation. The majority of SynCAM is localized to synaptic sites where it initiates synaptic assembly and synapse differentiation throughout the central nervous system. SynCAM also mediates the cellular adhesion of spermatogenic cells to Sertoli cells and mast cells to fibroblasts.
Related products CM004-3 Anti-SynCAM (TSLC1/CADM1) mAb
CM005-3 Anti-SynCAM (TSLC1/CADM1) (Human) mAb
CM004-A64 Anti-SynCAM (TSLC1/CADM1) mAb-Alexa Fluor® 647
CM004-4 Anti-SynCAM (TSLC1/CADM1) mAb-FITC
PM084 Normal Chicken IgY
PM084-4 Normal Chicken IgY-FITC
PM084-5 Normal Chicken IgY-PE
CM004-5 Anti-SynCAM (TSLC1/CADM1) mAb-PE
Citations

Immunoprecipitation

  1. Rademacher N et al. MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density. Sci Rep. 6, 35283 (2016)(PMID:27756895)

Flow Cytometry

  1. Balan S et al. Large-Scale Human Dendritic Cell Differentiation Revealing Notch-Dependent Lineage Bifurcation and Heterogeneity. Cell Rep. 24, 1902-1915.e6 (2018)(PMID:30110645)
  2. Cañete PF et al. Regulatory roles of IL-10-producing human follicular T cells. J Exp Med. 216, 1843-1856 (2019)(PMID:31209070)
  3. Makiyama J et al. CD4+ CADM1+ cell percentage predicts disease progression in HTLV-1 carriers and indolent adult T-cell leukemia/lymphoma. Cancer Sci. 110, 3746-3753 (2019) (PMID:31642546)
Product category
Research area
Cancer
Neuroscience
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 00:05, Jan 19, 2022 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.