Anti-Osteopontin (SPP1) (Human) mAb

Price

¥52,800

Availability (in Japan)

10 or more

（In Japan at 00:05,
Jan 24, 2025 in JST）

Size

100 µL (1 mg/mL)

Data	Flow Cytometry
Clonality	Monoclonal	Clone	4A7D
Isotype (Immunized Animal)	Mouse IgG2aκ
Applications	FCM 1-10 µg/mL
Immunogen (Antigen)	Human Osteopontin (SPP1) expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Reactivity [Gene ID]	Human[6696]
Storage buffer	1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp.	-20°C	Conjugate	Unlabeled	Manufacturer	MBL
Alternative names	OPN, BNSP, BSPI, ETA-1
Background	Osteopontin, also known as SPP1, is a secreted phosphoglycoprotein that belongs to the SIBLING family. Osteopontin binds to hydroxyapatite and is involved in anchoring of osteoclasts to the mineral matrix of bones. It also acts as a cytokine that mediates type I immune responses through enhancing the production of interferon-gamma and interleukin-12 while reducing production of interleukin-10. Osteopontin has been identified as a biomarker for ovarian cancer, prostate cancer, and non-small cell lung cancer.
Related products	M076-3 Mouse IgG2a (isotype control) MTG-001 Clear Back (Human Fc receptor blocking reagent) D050-3 Anti-CD29 (Integrin β1) (Human) mAb W164-3 Anti-RHBDD3 (Human) mAb
References	Kojima T, Kitamura T. A signal sequence trap based on a constitutively active cytokine receptor. Nat Biotechnol 17, 487-90 (1999)（PMID: 10331810）
Product category	Research area Stem cell research Cancer Cytokine & Growth Factors Tools Flow cytometry reagents

The availability is based on the information in Japan at 00:05, Jan 24, 2025 in JST.
The special price is shown in red color.
Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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