Price
¥52,800
Availability (in Japan)
1-9
(In Japan at 17:00,
Feb 9, 2025 in JST)
Size
100 µL (1 mg/mL)
Data | |||||
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Clonality | Monoclonal | Clone | C5 | ||
Isotype (Immunized Animal) | Mouse IgG2aκ | ||||
Applications |
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Immunogen (Antigen) | KLH-conjugated synthetic peptide, CPPAFNRPAPGAE (corresponding to amino acid residues 453-464 of mouse Nono) | ||||
Reactivity [Gene ID] | |||||
Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | ||||
Storage temp. | -20°C | Conjugate | Unlabeled | Manufacturer | MBL |
Alternative names | non-POU domain-containing octamer-binding protein nonA, NRB54, AA407051, AV149256 | ||||
Background | Nono, also known as p54nrb, localizes to nuclear paraspeckles composed of distinct membrane-less subnuclear organelles termed as nuclear bodies. Paraspeckles consist of some RNAs and proteins, and representative RNA component of paraspeckle is Neat1 long non-coding RNA, which can bind to Nono directly. Nono plays multiple roles in gene expression regulation systems such as transcription and splicing by binding to DNA and RNA via its coiled coil domain and RNA recognition motif, respectively. It is also reported that Nono relates to nuclear retention of “A-to-I edited” RNA. | ||||
Related products | RN014MW Anti-SFPQ (PSF) mAb RN092PW Anti-NONO (P54NRB) pAb M019-3 Anti-Nucleolin mAb M041-3 Anti-PML (Human) mAb PM064 Anti-Lamin B1 pAb PM091 Anti-Per1 (Mouse) pAb PM093 Anti-NR1D2 (Rev-erbβ) pAb |
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References |
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