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HOME > Product search results > Code No. PD010 Anti-ATBF1 (D1-120) pAb

Code No. PD010

Anti-ATBF1 (D1-120) pAb



Availability (in Japan)


(In Japan at 00:05,
Aug 13, 2020 in JST)


100 µL

  • Western Blotting

  • Immunoprecipitation

  • Immunocytochemistry

  • Immunohistochemistry

  • Immunohistochemistry

Clonality Polyclonal Clone Polyclonal
Isotype (Immunized Animal) Rabbit IgG
1 μL/150 μg of cell lysate  
Immunogen (Antigen) recombinant region of human ATBF1 (2107-2147 aa.) corresponding to the identical amino acid sequence of mouse ATBF1 (2114-2154 aa.)
Reactivity [Gene ID]

Human[463], Mouse[11906], Rat[307829]

Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names ZFHX3, ATBT, ZNF927
Background ATBF1 (also known as ZFHX3) is a transcription factor that has two-protein isoforms, the 404 kDa ATBF1-A and the 306 kDa ATBF1-B. ATBF1-A contains four homeodomains and 23 zinc-finger motifs.
ATBF1-B contains four homeodomains and 18 zinc fingers. ATBF1 is identified as DNA-binding protein, which binds to an AT-rich element of the human α-fetoprotein (AFP) gene, as a result suppressing its transcription activity. ATBF1 is also involved in cell cycle arrest and cooperating with p53 to activate the p21Waf1/Cip1 promoter. ATBF1 is expressed in the differentiation fields in association with β-tubulin III and MAP2 that are the neuronal differentiation marker. ATBF1 plays a crucial role in neuronal development and cell cycle arrest.
Related products PD011 Anti-ATBF1 (AT-6) pAb

Western Blotting

  1. Zhang S et al. AT motif binding factor 1 (ATBF1) is highly phosphorylated in embryonic brain and protected from cleavage by calpain-1. Biochem Biophys Res Commun. 427, 537-41 (2012)(PMID:23022192)
  2. Chen XH et al. Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis. Acta Pharmacol Sin. 40, 1568-1577 (2019)(PMID:31152485)
  3. Zhang Z et al. Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 322, 113055 (2019)(PMID:31491374)


  1. Kawaguchi M et al. A diagnostic marker for superficial urothelial bladder carcinoma: lack of nuclear ATBF1 (ZFHX3) by immunohistochemistry suggests malignant progression. BMC Cancer 16, 805 (2016)(PMID:27756245)


  1. Kim TS et al. The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress. Dis Model Mech. 3, 752-62 (2010)(PMID:20876357)
  2. Uhm KO et al. ATBF1 is a novel amyloid-β protein precursor (AβPP) binding protein that affects AβPP expression. J Alzheimers Dis. 43, 243-57 (2015)(PMID:25079792)
  3. Zhang Z et al. Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 322, 113055 (2019)(PMID:31491374)


  1. Jung CG et al. Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation. Development 132, 5137-45 (2005)(PMID:16251211)
Product category
Research area

  • The availability is based on the information in Japan at 00:05, Aug 13, 2020 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.