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HOME > Product search results > Code No. MEX004-6 Anti-CD326 (EpCAM) mAb-Biotin

Code No. MEX004-6

Anti-CD326 (EpCAM) mAb-Biotin



Special price


(ends 2020/03/31)


Availability (in Japan)


(In Japan at 00:05,
Jan 25, 2020 in JST)


50 µg/50 µL

  • Flow Cytometry





Clonality Monoclonal Clone B8-4
Isotype (Immunized Animal) Mouse IgG1 κ
5 µg/mL  
Can be used.  
Other(Exosome isolation)
Can be used.  
Reactivity [Gene ID]


Storage temp. 4°C Conjugate Biotin Manufacturer MBL
Alternative names ESA, KSA, M4S1, MK-1, DIAR5, EGP-2, EGP40, KS1/4, MIC18, TROP1, EGP314, HNPCC8, TACSTD1
Background The epithelial cell adhesion molecule (EpCAM), also known as a CD326, is a transmembrane glycoprotein and first discovered on human colon carcinoma. In addition, EpCAM is defined as a monoclonal antibody AUA1-reactive cell surface antigen. This type I membrane protein is expressed only on epithelial cells and highly expressed on most carcinoma such as colorectal carcinoma and gastric cancer. EpCAM plays a role in cell-to-cell adhesion by regulating its own homophilic interaction in a Ca2+ independent manner. It is reported that tumor-derived circulating exosomes, called Extracellular Vesicles (EVs) or microvesicles, can be easily isolated using anti-EpCAM antibody bound magnetic beads, followed by various down-stream analyses such as sandwich immunoassay and RT-qPCR to elucidate the tumor-specific exosome surface protein profile and associated miRNA.
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  1. Spurr NK et al. Characterization and chromosomal assignment of a human cell surface antigen defined by the monoclonal antibody AUAI. Int J Cancer. 38, 631-6 (1986)(PMID: 3770992
  2. Koga Y et al. Improved recovery of exfoliated colonocytes from feces using newly developed immunomagnetic beads. Gastroenterol Res Pract. 2008, 605273 (2008)(PMID: 19125182
  3. Taylor DD, Gercel-Taylor C. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol. Oncol. 110, 13-21 (2008)(PMID: 18589210
  4. Marhaba R et al. CD44 and EpCAM: cancer-initiating cell markers. Curr Mol Med. 8, 784-804 (2008)(PMID: 19075676
  5. Rabinowits G et al. Exosomal microRNA: a diagnostic marker for lung cancer. Clin Lung Cancer 10, 42-46 (2009)(PMID: 19289371
  6. van der Gun BT et al. EpCAM in carcinogenesis: the good, the bad or the ugly. Carcinogenesis 31, 1913-21 (2010)(PMID: 20837599
Product category
Research area
RNA-RNP Network
Cell surface antigens

  • The availability is based on the information in Japan at 00:05, Jan 25, 2020 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.