| Data |
Western Blotting

Immunoprecipitation

|
| Clonality |
Monoclonal
|
Clone |
6F8 |
|
Isotype
(Immunized Animal)
|
Rat IgG2a
|
| Applications |
- WB
- 1 µg/mL
 - IP
- 5 µg/350 µL of cell extract from 5x106 cells
 - FCM*
- reported. (PMID: 22541243)

|
| Immunogen
(Antigen) |
Recombinant Mouse full length TRAF2
|
| Reactivity
[Gene ID] |
Human[7186], Mouse[22030], Rat[311786] |
| Storage buffer |
1 mg/mL in PBS/50% glycerol, pH 7.2
|
| Storage temp. |
-20°C
|
Conjugate |
Unlabeled |
Manufacturer |
MBL |
| Alternative names |
TNF receptor-associated factor 2, MGC:45012, TRAP, TRAP3
|
| Related products |
597 Anti-TRAF6 (Mouse) pAb
|
| Citations |
Western Blotting - Haxhinasto SA et al. Cutting edge: molecular mechanisms of synergy between CD40 and the B cell antigen receptor: role for TNF receptor-associated factor 2 in receptor interaction. J Immunol. 169, 1145-9 (2002)(PMID:12133933)
- Jabara HH et al. TRAF2 and TRAF3 independently mediate Ig class switching driven by CD40. Int Immunol. 21, 477-88 (2009)(PMID:19228877)
- Cheung TC et al. Unconventional ligand activation of herpesvirus entry mediator signals cell survival. PNAS 106, 6244-9 (2009)(PMID:19332782)
- Cheung TC et al. T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment. J Immunol. 183, 7286-96 (2009)(PMID:19915044)
Immunoprecipitation - Sanjo H et al. Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor. J Biol Chem. 285, 17148-55 (2010)(PMID:20348096)
- So T et al. OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signaling. J Immunol. 186, 3547-55 (2011)(PMID:21289304)
Flow Cytometry - Iwata S et al. Amplification of Toll-like receptor-mediated signaling through spleen tyrosine kinase in human B-cell activation. J Allergy Clin Immunol. 129, 1594-601 (2012)(PMID:22541243)
|
| Product category |
- Research area
- Immunology
Cancer Apoptosis
|