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HOME > Product search results > Code No. M068-3 Anti-Apolipoprotein E (Human) mAb

Code No.　M068-3

Anti-Apolipoprotein E (Human) mAb

Price

¥52,800

Availability (in Japan)

10 or more

（In Japan at 00:05,
Apr 20, 2024 in JST）

Size

100 µL (1 mg/mL)

Data

  • Western Blotting
Clonality Monoclonal Clone 3D12
Isotype (Immunized Animal) Mouse IgG2a
Applications
WB
1 µg/mL  
IP
5 μg/2 μL of human serum  
IH
reported.  
Immunogen (Antigen) Recombinant Human Apolipoprotein E3
Reactivity [Gene ID]

Human[348], Mouse(-), Rat(-), Rabbit(-), Bovine(-)
Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names APOE
Background Apolipoprotein E (ApoE), a 35 kDa　plasma protein containing sialic acid, plays a role in　triglyceride, cholesterol transport and metabolism, and　known to be synthesized in liver, brain and other organs.　ApoE is a polymorphic apolipoprotein exhibiting three　isoforms such as Apo E2, E3 and E4 coded for by three　alleles of ε2, ε3 and ε4 at a single gene locus respectively.
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Citations

Western Blotting

  1. He X et al. Apolipoprotein receptor 2 and X11 alpha/beta mediate apolipoprotein E-induced endocytosis of amyloid-beta precursor protein and beta-secretase, leading to amyloid-beta production. J Neurosci. 27, 4052-60 (2007)(PMID:17428983)

  2. Lindén M et al. Proteomic analysis of urinary biomarker candidates for nonmuscle invasive bladder cancer. Proteomics 12, 135-44 (2012)(PMID:22065568)

Immunohistochemistry

  1. Lindén M et al. Proteomic analysis of urinary biomarker candidates for nonmuscle invasive bladder cancer. Proteomics 12, 135-44 (2012)(PMID:22065568)

  2. Lindén M et al. Tumour expression of bladder cancer-associated urinary proteins. BJU Int. 112, 407-15 (2013)(PMID:23470167)
  3. Zhang G et al. Validation and clinicopathologic associations of a urine-based bladder cancer biomarker signature. Diagn Pathol. 9, 200 (2014)(PMID:25387487)
  4. Levy O et al. Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration. EMBO Mol Med. 7, 211-26 (2015)(PMID:25604058)
  5. Furuya H et al. Prognostic Significance of Lymphocyte Infiltration and a Stromal Immunostaining of a Bladder Cancer Associated Diagnostic Panel in Urothelial Carcinoma. Diagnostics (Basel) 10, 14 (2019) (PMID:31905599)
Product category
Research area
Neuroscience
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 00:05, Apr 20, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.