Price
¥41,800
Availability (in Japan)
10 or more
(In Japan at 00:05,
Jan 24, 2025 in JST)
Size
100 µL (1 mg/mL)
Data | |||||
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Clonality | Monoclonal | Clone | EMR8-5 | ||
Isotype (Immunized Animal) | Mouse IgG1 κ | ||||
Applications |
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Immunogen (Antigen) | Recombinant HLA-A*2402 extracellular domain | ||||
Reactivity [Gene ID] | |||||
Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | ||||
Storage temp. | -20°C | Conjugate | Unlabeled | Manufacturer | MBL |
Alternative names | major histocompatibility complex, class I, HLA-A, HLAA/HLA-B, AS, HLAB, SPDA1/HLC-C, D6S204, PSORS1, HLA-JY3 | ||||
Background | Human major histocompatibility complex (MHC) class I antigen-epitope peptide complex associated with β2-microglobulin are expressed by all human nucleated cells. It plays an important role in cell-mediated immune responses. Abnormalities in MHC class I antigen surface expression are frequently found in malignancies and infectious diseases. They are often associated with reduced recognition by MHC class I antigen-restricted, tumor or virus-associated antigen-specific cytotoxic T lymphocytes and disease progression. The EMR8-5 monoclonal antibody reacts with a non-polymorphic epitope of human MHC class I antigens, HLA-A, -B, and -C. | ||||
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