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HOME > Product search results > Code No. D299-3 Anti-IDH1-R132H (Human) mAb

Code No. D299-3

Anti-IDH1-R132H (Human) mAb

Price

¥34,000

Availability (in Japan)

10 or more

(In Japan at 00:05,
Nov 17, 2019 in JST)

Size

100 µg/100 µL

This clone reacts with mutated IDH1-R132H and does not cross-react with wild type IDH1 and other IDH1 mutants.
Data
  • Western Blotting

  • Immunohistochemistry

Clonality Monoclonal Clone HMab-1
Isotype (Immunized Animal) Mouse IgG1 κ
Applications
WB
5-10 µg/mL  
IP
10 µg/100 µg Lysate  
IC
  
IH
5 µg/mL  
Reactivity [Gene ID]

Human[3417](PMID: 22396072), Hamster(-), Dog*[478889](PMID: 29285579)

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names isocitrate dehydrogenase 1 (NADP+), soluble
Related products D309-3 Anti-IDH1 mAb
D300-3 Anti-IDH1-R132S (Human) mAb
D328-3 Anti-IDH2-R172K (Human) mAb
D330-3 Anti-IDH2 mAb
D331-3 Anti-IDH1-R132G (Human) mAb
D336-3 Anti-IDH1 mAb
D337-3 Anti-IDH2-R172M (Human) mAb
D338-3 Anti-IDH2-R172W (Human) mAb
D332-3 Anti-Mutated IDH1/2 (Human) mAb
Citations

Western Blotting

  1. Kawakami S et al. R132 mutations in canine isocitrate dehydrogenase 1 (IDH1) lead to functional changes. Vet Res Commun. 42, 49-56 (2018)(PMID:29285579)
  2. Li S et al. Mutation of IDH1 aggravates the fatty acid‑induced oxidative stress in HCT116 cells by affecting the mitochondrial respiratory chain. Mol Med Rep. 19, 2509-2518 (2019)(PMID:30720071)

Immunocytochemistry

  1. Kawakami S et al. R132 mutations in canine isocitrate dehydrogenase 1 (IDH1) lead to functional changes. Vet Res Commun. 42, 49-56 (2018)(PMID:29285579)

Immunohistochemistry

  1. Takano S et al. Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors. J Neurooncol. 108, 361-73 (2012)(PMID:22396072)
  2. Ishikawa E et al. Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma. J Neurosurg. 121, 543-53 (2014)(PMID:24995786)
  3. Fukami S et al. Pathologic Findings and Clinical Course of Midline Paraventricular Gliomas Diagnosed Using a Neuroendoscope. World Neurosurg. 114, e366-e377 (2018)(PMID:29530692)
  4. Liu R et al. Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance. Nat Commun. 10, 991 (2019) (PMID:30824700)
Product category
Research area
Cancer
Neuroscience
Tools
Molecular pathology tools
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  • The availability is based on the information in Japan at 00:05, Nov 17, 2019 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.