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HOME > Product search results > Code No. D219-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide)

Code No. D219-3

Anti-Desmoglein 3 (Mouse) mAb (No Azide)

Price

¥52,000

Availability (in Japan)

10 or more

(In Japan at 00:05,
Jan 20, 2020 in JST)

Size

100 µg/100 µL

Data
  • Immunocytochemistry

  • Immunohistochemistry

  • Immunohistochemistry

Clonality Monoclonal Clone AK23
Isotype (Immunized Animal) Mouse IgG1
Applications
IP*
reported.  (PMID: 12574390
IC
1 µg/mL  
IH
1 µg/mL  
Immunogen (Antigen) hybridoma was established by fusion of splenocytes from PV model mouse and P3 mouse myeloma cells
Reactivity [Gene ID]

Human[1830], Mouse[13512]

Storage buffer 1 mg/mL in PBS, pH 7.2
Storage temp. 4°C Conjugate Unlabeled Manufacturer MBL
Alternative names Dsg3
Background Pemphigus vulgaris (PV) is a life -threatening autoimmune blistering disease of the skin and mucous membranes. In patients of PV, IgG autoantibodies against the cell surface of keratinocytes in stratified squamous epithelia play a major pathogenic role in loss of cell-cell adhesion. The autoimmune target of PV is desmoglein 3 (Dsg3), which is a member of the cadherin family of calcium-depending, transmembrane glycoprotein.
Related products D217-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide)
D218-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide)
Citations

Immunoprecipitation

  1. Tsunoda K, et al., Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3. J Immunol. 170:2170-8. 2003(PMID:12574390)

Immunohistochemistry

  1. Tsunoda K, et al., Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3. J Immunol. 170:2170-8. 2003(PMID:12574390)
References
  1. Tsunoda K et al. Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3. J Immunol. 170, 2170-8 (2003)(PMID: 12574390
Product category
Research area
Immunology
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  • The availability is based on the information in Japan at 00:05, Jan 20, 2020 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.