Price
¥66,000
Availability (in Japan)
1-9
(In Japan at 00:05,
Jan 17, 2025 in JST)
Size
50 µL
Data | |||||
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Clonality | Polyclonal | Clone | polyclonal | ||
Isotype (Immunized Animal) | Rabbit Ig (aff.) | ||||
Applications |
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Immunogen (Antigen) | Human SLC40A1-derived synthetic peptide | ||||
Reactivity [Gene ID] | Human[30061] |
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Storage buffer | PBS/50% glycerol, pH 7.2 | ||||
Storage temp. | -20°C | Conjugate | Unlabeled | Manufacturer | MBL |
Alternative names | solute carrier family 40 member 1, ferroportin 1 | ||||
Background | SLC40A1, also known as ferroportin 1, belongs to the iron-regulated transporter family and absorbs iron from the diet into the bloodstream through the small intestine. The absorbed iron binds to transferrin in the blood and is then carried to tissues and organs throughout the body. SLC40A1 also transports iron out of reticuloendothelial cells, which are phagocytic immune cells present in the liver, spleen, and bone marrow. Mutations in the <em>SLC40A1</em> gene cause hemochromatosis, which is characterized by impaired iron regulation and disorders associated with iron deficiency or overload. |