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HOME > Product search results > Code No. B-NU856UC Anti-GCDFP-15 mAb

Code No. B-NU856UC

Anti-GCDFP-15 mAb



Availability (in Japan)

(Contact us)

(In Japan at 00:05,
Dec 9, 2019 in JST)


1 mL

  • Immunohistochemistry

    Breast cancer tissue stained with Anti-GCDFP-15 using DAB chromogen

Clonality Monoclonal Clone EP95
Isotype (Immunized Animal) Rabbit IgG
Reactivity [Gene ID]


Storage buffer PBS/1% BSA/0.09% NaN3
Storage temp. 4°C Conjugate Unlabeled Manufacturer BIOGENEX LABORATORIES,INC
Background Gross cystic disease fluid protein (GCDFP-15), also called prolactin inducible protein (PIP), is a single polypeptide chain with a versatile function in human reproductive and immunological systems. GCDFP-15 binds to CD4, exerts a potent inhibition on T lymphocyte apoptosis mediated by CD4/T-cell receptor (TCR) activation, and carries a fibronectin-specific aspartyl protease activity. It is up regulated by prolactin and androgens, while it is down regulated by estrogen. In normal adult tissues, GCDFP-15 expression was found in all apocrine, lacrimal, ceruminous, and Moll’s glands and in numerous serous cells of the submandibular, sublingual, and minor salivary glands. The serous cells of nasal and bronchial glands were also positive. It is used as a marker of apocrine differentiation. GCDFP-15 has been found in the cyst fluid of cystic breast disease and primary and metastatic breast cancer, and considered a highly specific marker for identification of breast cancer. GCDFP-15 expression has also been found in other cancer types including salivary glands, sweat glands, prostate, and lung.
Product category
Molecular pathology tools

  • The availability is based on the information in Japan at 00:05, Dec 9, 2019 in JST.
  • The special price is shown in red color.
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  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
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