Price
¥121,400
Availability (in Japan)
0
(Contact us)
(In Japan at 00:05,
Dec 9, 2019 in JST)
Size
1 mL
Data | |||||
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Clonality | Monoclonal | Clone | 4A4 | ||
Isotype (Immunized Animal) | Mouse IgG2a | ||||
Applications |
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Reactivity [Gene ID] | Human |
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Storage buffer | PBS/1% BSA/0.09% NaN3 | ||||
Storage temp. | 4°C | Conjugate | Unlabeled | Manufacturer | BIOGENEX LABORATORIES,INC |
Background | This antibody will detect all isoforms of p63 since the epitope is within the DNA binding domain. The p63 protein is a member of the p53 family, which also includes p73. p63 protein is detected in proliferating cells of epithelium, cervix, urothelium and prostate. It is also expressed in most poorly differentiated squamous cell carcinomas. The delta Np63 isoform is also abundantly expressed in nasopharyngeal carcinomas. The predominant localization of p63 protein is in the basal layer of stratified squamous and transitional epithelia. p63 is also an essential gene that is critical for regenerative proliferation of cells involved in limb, craniofacial and epidermal morphogenesis. | ||||
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