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HOME > Product search results > Code No. B-AN7385M Anti-NGFR mAb

Code No. B-AN7385M

Anti-NGFR mAb

Price

¥102,100

Availability (in Japan)

0
(Contact us)

(In Japan at 17:00,
Dec 8, 2019 in JST)

Size

6 mL

Data
  • Immunohistochemistry

    Brain tissue stained with Anti-NGFR using DAB chromogen

Clonality Monoclonal Clone EP31
Isotype (Immunized Animal) Rabbit IgG
Applications
IH
Ready-to-Use  
Reactivity [Gene ID]

Human

Storage buffer PBS/1% BSA/0.09% NaN3
Storage temp. 4°C Conjugate Unlabeled Manufacturer BIOGENEX LABORATORIES,INC
Background NGFR (Nerve Growth Factor Receptor), also termed p75 or CD271, is the low-affinity NGFR (LNGFR) which binds NGF and other neutrophils, including BDNF, NT3 and NT4/5 with similar low-affinity. It is expressed in neuronal cells in various tissues and tumors with neuronal origin. Recent studies suggested that NGFR is also expressed in melanocytes, myoepithelial cells, basal-like cells, perivascular cells and lymphoid dendritic cells. NGFR is expressed not only in sympathetic and sensory neurons, but also in various neural crest cells or tumor derivatives such as melanocytes, Melanomas, Neurobastomas, Pheochromocytomas, Neurofibromas and neurotized nevi (Type C Melanocytes). It is now apparent that expression of NGFR is ubiquitous and not limited to the nervous system. Studies in Prostate and Urothelial cancer suggest that NGFR may act as a tumor suppressor, negatively regulating cell growth and proliferation. NGFR labels the myoepithelial cells of breast ducts and intralobular fibroblasts of breast ducts and thus aids in the diagnosis of malignancy in the breast.
Product category
Tools
Molecular pathology tools
Brands
BioGenex
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  • The availability is based on the information in Japan at 17:00, Dec 8, 2019 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.