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HOME > Product search results > Code No. B-AN5385M Anti-P504S (AMACR) mAb

Code No. B-AN5385M

Anti-P504S (AMACR) mAb



Availability (in Japan)

(Contact us)

(In Japan at 00:05,
Dec 9, 2019 in JST)


6 mL

  • Immunohistochemistry

    Prostate carcinoma stained with Anti-P504S using DAB chromogen

Clonality Monoclonal Clone RBT-AMACR
Isotype (Immunized Animal) Rabbit IgG
Reactivity [Gene ID]


Storage temp. 4°C Conjugate Unlabeled Manufacturer BIOGENEX LABORATORIES,INC
Background AMACR (P504S) is an acronym for the protein alpha-methylacyl CoA racemase that helps to metabolize certain fatty acids within the body. AMACR has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. High expression of AMACR (P504S) protein is usually found in prostatic adenocarcinoma but not in benign prostatic tissue by immunohistochemical staining in paraffin-embedded tissues. It stains premalignant lesions of prostate: high grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. Several studies have suggested that AMACR can be used as a prostate cancer biomarker. Using AMACR (P504S) as a positive marker along with basal cell staining (34 or p63) as a negative marker could help to confirm the diagnosis of small focus of prostate carcinoma on needle biopsies.
Product category
Molecular pathology tools

  • The availability is based on the information in Japan at 00:05, Dec 9, 2019 in JST.
  • The special price is shown in red color.
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  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
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