Code No. |
CY-1170 |
CycLex® CK2(Casein kinase II) Kinase Assay/Inhibitor Screening Kit
|
価格(税別) |
¥99,000
|
包装 |
96 assays |
在庫 |
1-9
(2025/04/25 00:05時点)
|
キット構成品 |
Microplate, 10x Wash Buffer, Kinase Buffer, 20x ATP, HRP conjugated Detection Antibody, Substrate Reagent, Stop Solution |
使用目的 |
This Kit designed to measure the activities of purified CK2 for the rapid and sensitive evaluation of inhibitors or activators. |
保存温度 |
4°C |
メーカー |
MBL |
関連製品 |
CY-E1170-1 CK2 (alpha/beta) Positive Control
|
製品カテゴリー |
分野:ドラッグディスカバリー シグナル伝達 |
使用文献 |
- Wang G et al. Protein B23/Nucleophosmin/Numatrin nuclear dynamics in Relation to Protein Kinase CK2 and Apoptotic Activity in Prostate Cells. Biochemistry, 49: 3842-3852 (2010)(PMID:20387789)
- Oinuma I et al. Semaphorin 4D/Plexin-B1 Stimulates PTEN Activity through R-Ras GTPase-activating Protein Activity, Inducing Growth Cone Collapse in Hippocampal Neurons. J Biol Chem. 285, 28200-28209 (2010)(PMID:20610402)
- Lee WH et al. Casein kinase 2 regulates the mRNA-destabilizing activity of tristetraprolin. J Biol Chem. 286, 21577-21587 (2011)(PMID:21507959)
- Lee HR et al. Attenuation of β-amyloid-induced tauopathy via activation of CK2α/SIRT1: targeting for cilostazol. J Neurosci Res. 92, 206-17 (2014)(PMID:24254769)
- Jung EB et al. Casein kinase 2 inhibition attenuates cholesterol oxidation product-induced apoptosis by suppressing the activation of the mitochondrial pathway and the caspase-8- and bid-dependent pathways. Neurochem Int. 65, 30-9 (2014)(PMID:24398405)
- de Thonel A et al. Regulation of the proapoptotic functions of prostate apoptosis response-4 (Par-4) by casein kinase 2 in prostate cancer cells. Cell Death Dis. 5, e1016 (2014)(PMID:24457960)
- Lee YS et al. Helicobacter pylori induces cell migration and invasion through casein kinase 2 in gastric epithelial cells. Helicobacter. 19, 465-75 (2014)(PMID:25052887)
- Zhang Q et al. CK2 Phosphorylating I2PP2A/SET Mediates Tau Pathology and Cognitive Impairment. Front Mol Neurosci. 11, 146 (2018)(PMID:29760653)
- Floris A et al. Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression. J Exp Clin Cancer Res. 38, 4. (2019)(PMID:30611309)
- Im J, Nho RS. Fibroblasts from patients with idiopathic pulmonary fibrosis are resistant to cisplatin-induced cell death via enhanced CK2-dependent XRCC1 activity. Apoptosis. 24, 499-510 (2019)
(PMID:30850922)
|