抗体 製品詳細情報

Code No. M181-3
Anti-KDEL mAb
価格(税別) ¥27,500
包装 100 µL (1 mg/mL)
在庫 10以上
(2024/04/24 00:05時点)
クローナリティー Monoclonal
クローン 1D5
アイソタイプ
(免疫動物)
Mouse IgG2aκ
使用法 WB 0.1 µg/mL  
IP* reported.  (PMID: 21072203)
IC 
IH* reported.  (PMID: 19760141)
IF* reported.  
Other(In Situ PLA) reported.  (PMID: 32901097)
免疫原(抗原) Mouse GRP78 C-terminal 644-655 aa
交差性 [Gene ID]

Human, Mouse, Rat, Hamster, Fruit fly*(PMID: 23318643)

性状 1 mg/mL in PBS/50% glycerol, pH 7.2
保存温度 -20°C
標識 Unlabeled
メーカー MBL
背景 The KDEL (lys-asp-glu-leu) sequence is most common endoplasmic reticulum (ER) retention signal. The ER resident proteins, which should be located in the ER, have this retention motif, and this retention is mediated by KDEL receptor.
関連製品 PM059 Anti-KDEL pAb
M178-3 Anti-Calnexin mAb
PM060 Anti-Calnexin pAb
M176-3 Anti-EEA1 mAb
PM062 Anti-EEA1 pAb
M179-3 Anti-GM130 mAb
PM061 Anti-GM130 pAb
PM064 Anti-Lamin B1 pAb
製品カテゴリー ツール:その他
データ


使用文献

Western Blotting

  1. Xiang Y et al. Lactic acid induces aberrant amyloid precursor protein processing by promoting its interaction with endoplasmic reticulum chaperone proteins. PLoS One. 5, e13820 (2010)(PMID:21072203)
  2. Yagyu K et al. Activation of protein kinase R in the manganese-induced apoptosis of PC12 cells. Toxicology. 442, 152526 (2020)(PMID:32574669)

Immunoprecipitation

  1. Xiang Y et al. Lactic acid induces aberrant amyloid precursor protein processing by promoting its interaction with endoplasmic reticulum chaperone proteins. PLoS One. 5, e13820 (2010)(PMID:21072203)

Immunocytochemistry

  1. Xiang Y et al. Lactic acid induces aberrant amyloid precursor protein processing by promoting its interaction with endoplasmic reticulum chaperone proteins. PLoS One. 5, e13820 (2010)(PMID:21072203)
  2. Zhang B et al. Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin. Blood 118, 3384-91 (2011)(PMID:21795745)
  3. van de Hoef DL et al. FKBP14 is an essential gene that regulates Presenilin protein levels and Notch signaling in Drosophila. Development 140, 810-9 (2013)(PMID:23318643)
  4. Zhao C et al. Mice lacking the intracellular cation channel TRIC-B have compromised collagen production and impaired bone mineralization. Sci Signal. 9, ra49 (2016)(PMID:27188440)

Immunohistochemistry

  1. Hino S et al. Regulation of ER molecular chaperone prevents bone loss in a murine model for osteoporosis. J Bone Miner Metab. 28, 131-8 (2010)(PMID:19760141)
  2. Furuichi T et al. ENU-induced missense mutation in the C-propeptide coding region of Col2a1 creates a mouse model of platyspondylic lethal skeletal dysplasia, Torrance type. Mamm Genome. 22, 318-28 (2011)(PMID:21538020)

Immunofluorescence

  1. Naoto Matsumoto N et al. PP1C and PP2A are p70S6K Phosphatases Whose Inhibition Ameliorates HLD12-Associated Inhibition of Oligodendroglial Cell Morphological Differentiation. Biomedicines. 8, 89 (2020)(PMID:32316234)
  2. Ninagawa S et al. Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes. Elife. 9, e60970 (2020)(PMID:33198886)

ELISA

  1. Nakanishi K et al. Plant-derived secretory component forms secretory IgA with shiga toxin 1-specific dimeric IgA produced by mouse cells and whole plants. Plant Cell Rep. 38, 161-172 (2019)(PMID:30506369)

Other(In Situ PLA)

  1. Yoshimoto S et al. NFAT5 promotes oral squamous cell carcinoma progression in a hyperosmotic environment. Lab Invest. 101, 38-50 (2021)(PMID:32901097)

※在庫につきましては2024年04月24日 00時05分時点における在庫数を表示してあります。
※価格の赤色表示につきましては、キャンペーン価格の表示となっております。
※このサイトからは直接注文はできません。ご注意ください。
※使用法の表記について:
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation,
FCM: Flow Cytometry NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation,
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation,
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization

ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
※使用法・交差性の表記について:
*: 論文で報告されております(MBLでは未確認)。詳しくはデータシートをご覧ください。
**: 導入元からの情報です(MBLでは評価中もしくは未確認)。
※保存温度の表記について: RT: 室温
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