トップ > 製品検索結果一覧 > Code No. MEX001-12 Anti-CD9 mAb-ALP

Code No. MEX001-12

Anti-CD9 mAb-ALP

価格(税別)

¥58,000

在庫

10以上

(2019/11/13 17:00時点)

包装

50 µL

データ
  • ELISA

  • ELISA

クローナリティー Monoclonal クローン A100-4
アイソタイプ
(免疫動物)
Mouse IgG2aκ
使用法
ELISA
1:2,000  
免疫原(抗原) Human prostate carcinoma cell line (PC3) derived exosomes (prepared by ultracentrifugation from cultured supernatant)
交差性
[Gene ID]

Human[928]

性状 50 mM Tris-HCl, 100 mM NaCl, 1% BSA, 0.1% ProClin150 containing stabilizers
保存温度 4°C 標識 AP メーカー MBL
別称 5H9, BA2, BTCC-1, DRAP-27, GIC2, MIC3, MRP-1, P24, TSPAN29
背景 CD9, a member of the tetraspanin or transmembrane 4 super family (TM4SF; CD37, CD53, CD63, CD81, CD82, etc) of proteins, is widely distributed on the surface of a variety of hematopoietic and epithelial cell types. Several members of the tetraspanin family, including CD9, form noncovalent associations with integrins, particularly β1 integrins. CD9 and other tetraspanins have been postulated to participate in the regulation of cell growth, motility, and signaling via their physical association with integrins. CD9 has broad tissue distribution and may play multiple roles in a variety of cellular processes such as immune response and tumorigenesis, but its function has not been elucidated entirely. It is reported that the tetraspanins CD9, CD63 and CD81 are highly enriched on a certain type of extracellular vesicles, called exosome. Because of various exosome features, CD9, one of the representative exosome surface proteins, is thought to be related to cell-cell communication.
関連製品 MEX001-3 Anti-CD9 mAb
MEX001-4 Anti-CD9 mAb-FITC
MEX001-6 Anti-CD9 mAb-Biotin
MEX002-3 Anti-CD63 (LAMP-3) mAb
MEX002-4 Anti-CD63 (LAMP-3) mAb-FITC
MEX002-6 Anti-CD63 (LAMP-3) mAb-Biotin
MEX002-12 Anti-CD63 (LAMP-3) mAb-ALP
MEX003-3 Anti-CD81 (TAPA1) mAb
MEX003-4 Anti-CD81 (TAPA1) mAb-FITC
MEX003-6 Anti-CD81 (TAPA1) mAb-Biotin
MEX003-12 Anti-CD81 (TAPA1) mAb-ALP
MEX004-6 Anti-CD326 (EpCAM) mAb-Biotin
MEX-E ExoCap™ Nucleic Acid Elution Buffer
MEX-SA ExoCap™ Streptavidin Kit
参考文献
  1. Boucheix C et al. Molecular cloning of the CD9 antigen. A new family of cell surface proteins. J Biol Chem. 266, 117-22 (1991)(PMID: 1840589
  2. Simons M, Raposo G. Exosomes--vesicular carriers for intercellular communication. Curr Opin Cell Biol. 21, 575-81 (2009)(PMID: 19442504
  3. Pols MS, Klumperman J. Trafficking and function of the tetraspanin CD63. Exp Cell Res. 315, 1584-92 (2009)(PMID: 18930046
  4. Yoshioka Y et al. Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen. Nat Commun. 5, 3591 (2014)(PMID: 24710016
  5. Melo SA et al. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature 523, 177-82 (2015)(PMID: 26106858
製品
カテゴリー
分野
RNA-RNPネットワーク
がん
細胞膜表面抗原
エクソソーム
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※在庫につきましては2019年11月13日 17時00分時点における在庫数を表示してあります。
※価格の赤色表示につきましては、キャンペーン価格の表示となっております。
※このサイトからは直接注文はできません。ご注意ください。
※使用法の表記について:
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation,
FCM: Flow Cytometry NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation,
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
※使用法・交差性の表記について:
*: 論文で報告されております(MBLでは未確認)。詳しくはデータシートをご覧ください。
**: 導入元からの情報です(MBLでは評価中もしくは未確認)。
※保存温度の表記について: RT: 室温
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