This Lamin B1 polyclonal antibody is an effective nuclear envelope marker for Immunocytochemistry, Western blotting and Immunoprecipitation.
データ |
Western Blotting
Immunoprecipitation
Immunocytochemistry
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クローナリティー |
Polyclonal
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クローン |
Polyclonal |
アイソタイプ (免疫動物)
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Rabbit Ig (aff.)
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使用法 |
- WB
- 1:1,000
- IP
- 5 µL/300 µL of cell extract from 3 x 106 cells
- IC
- 1:200
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免疫原(抗原) |
KLH conjugated synthetic peptide corresponding to C-terminus of human Lamin B1
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交差性
[Gene ID] |
Human[4001], Mouse[16906], Rat[116685], Hamster[103161362]
|
性状 |
PBS/50% glycerol, pH 7.2
|
保存温度 |
-20°C
|
標識 |
Unlabeled |
メーカー |
MBL |
別称 |
ADLD, LMN, LMN2, LMNB
|
背景 |
Lamin B1 is one of the component proteins of the nuclear lamina that is a dense fibrous network and lies on the inner surface of the inner nuclear membrane. The nuclear lamina plays an essential role in chromatin organization, cell cycle regulation, DNA replication, cell differentiation and apoptosis.
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関連製品 |
RN014MW Anti-SFPQ (PSF) mAb M041-3 Anti-PML (Human) mAb RN013MW Anti-Nono (P54NRB) mAb PM088 Anti-Vinculin pAb PM059 Anti-KDEL pAb M181-3 Anti-KDEL mAb PM060 Anti-Calnexin pAb M178-3 Anti-Calnexin mAb PM061 Anti-GM130 pAb M179-3 Anti-GM130 mAb PM062 Anti-EEA1 pAb PM063 Anti-COX4 pAb
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使用文献
|
使用文献募集中!本製品を使って論文を発表されましたら是非お知らせください。
Western Blotting - Jia X et al. The modulation of hepatic adenosine triphosphate and inflammation by eicosapentaenoic acid during severe fibrotic progression in the SHRSP5/Dmcr rat model. Life Sci. 90, 934-43 (2012)(PMID:22569299)
- Jia X et al. Dysregulated bile acid synthesis, metabolism and excretion in a high fat-cholesterol diet-induced fibrotic steatohepatitis in rats. Dig Dis Sci. 58, 2212-22 (2013)(PMID:23824403)
- Yamamoto N et al. Polymerase complex with lysine at position 627 of the PB2 of influenza virus A/Hong Kong/483/97 (H5N1) efficiently transcribes and replicates virus genes in mouse cells. Virus Res. 178, 404-10 (2013)(PMID:24070983)
- Mukai R, Ohshima T. HTLV-1 HBZ positively regulates the mTOR signaling pathway via inhibition of GADD34 activity in the cytoplasm.Oncogene 33, 2317-28 (2014)23708656(PMID:23708656)
- Qu L et al. hCINAP negatively regulates NF-κB signaling by recruiting the phosphatase PP1 to deactivate IKK complex. J Mol Cell Biol. 7, 529-42 (2015)(PMID:26089539)
- Bai D et al. The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth. Nat Commun. 7, 12310 (2016)(PMID:27477389)
- Hirano K, Namihira M. FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1. FEBS Open Bio. 7, 1932-1942 (2017)(PMID:29226080)
- Mizunoe Y et al. Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways. Redox Biol. 15, 115-124 (2017)(PMID:29241092)
- Kaneko H et al. Taurine is an amino acid with the ability to activate autophagy in adipocytes. Amino Acids. 50, 527-535 (2018)(PMID:29523960)
- Endo H et al. Glucose starvation induces LKB1-AMPK-mediated MMP-9 expression in cancer cells. Sci Rep. 8, 10122 (2018)(PMID:29973599)
- Fujii N et al. Impact of aging and caloric restriction on fibroblast growth factor 21 signaling in rat white adipose tissue. Exp Gerontol. 118, 55-64 (2019)
(PMID:30620889)
- Xu R et al. hCINAP regulates the DNA-damage response and mediates the resistance of acute myelocytic leukemia cells to therapy. Nat Commun. 10, 3812 (2019)(PMID:31444354)
- Mizunoe Y et al. Cathepsin B Overexpression Induces Degradation of Perilipin 1 to Cause Lipid Metabolism Dysfunction in Adipocytes. Sci Rep. 10, 634 (2020)(PMID:31959889)
- Endo H et al. Metabolic reprogramming sustains cancer cell survival following extracellular matrix detachment. Redox Biol. 36, 101643 (2020)(PMID:32863227)
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製品
カテゴリー |
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※在庫につきましては2024年09月08日 00時05分時点における在庫数を表示してあります。
※価格の赤色表示につきましては、キャンペーン価格の表示となっております。
※このサイトからは直接注文はできません。ご注意ください。
※使用法の表記について:
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation,
FCM: Flow Cytometry NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation,
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
※使用法・交差性の表記について:
*: 論文で報告されております(MBLでは未確認)。詳しくはデータシートをご覧ください。
**: 導入元からの情報です(MBLでは評価中もしくは未確認)。
※保存温度の表記について: RT: 室温
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