トップ > 製品検索結果一覧 > Code No. MEX004-6 Anti-CD326 (EpCAM) mAb-Biotin

Code No. MEX004-6

Anti-CD326 (EpCAM) mAb-Biotin

価格(税別)

¥32,000

在庫

1-9

(2019/11/16 00:05時点)

包装

50 µg/50 µL

データ
  • Flow Cytometry

  • ELISA

    swCLEIA

  • ELISA

    swCLEIA

クローナリティー Monoclonal クローン B8-4
アイソタイプ
(免疫動物)
Mouse IgG1 κ
使用法
FCM
5 µg/mL  
ELISA
Can be used. Please refer to "ExoDiluent for Immunoassay (MEX1001)"together.  
Other(Exosome isolation)
Can be used.  
交差性
[Gene ID]

Human[4072]

保存温度 4°C 標識 Biotin メーカー MBL
別称 ESA, KSA, M4S1, MK-1, DIAR5, EGP-2, EGP40, KS1/4, MIC18, TROP1, EGP314, HNPCC8, TACSTD1
背景 The epithelial cell adhesion molecule (EpCAM), also known as a CD326, is a transmembrane glycoprotein and first discovered on human colon carcinoma. In addition, EpCAM is defined as a monoclonal antibody AUA1-reactive cell surface antigen. This type I membrane protein is expressed only on epithelial cells and highly expressed on most carcinoma such as colorectal carcinoma and gastric cancer. EpCAM plays a role in cell-to-cell adhesion by regulating its own homophilic interaction in a Ca2+ independent manner. It is reported that tumor-derived circulating exosomes, called Extracellular Vesicles (EVs) or microvesicles, can be easily isolated using anti-EpCAM antibody bound magnetic beads, followed by various down-stream analyses such as sandwich immunoassay and RT-qPCR to elucidate the tumor-specific exosome surface protein profile and associated miRNA.
関連製品 MEX002-6 Anti-CD63 (LAMP-3) mAb-Biotin
MEX003-6 Anti-CD81 (TAPA1) mAb-Biotin
MEX001-3 Anti-CD9 mAb
MEX002-3 Anti-CD63 (LAMP-3) mAb
MEX003-3 Anti-CD81 (TAPA1) mAb
MEX-E ExoCap™ Nucleic Acid Elution Buffer
3190 Magnetic Rack
MEX001-6 Anti-CD9 mAb-Biotin
M075-6 Mouse IgG1 (isotype control)-Biotin
MEX-SA ExoCap™ Streptavidin Kit
MEX001-4 Anti-CD9 mAb-FITC
MEX002-4 Anti-CD63 (LAMP-3) mAb-FITC
MEX003-4 Anti-CD81 (TAPA1) mAb-FITC
MEX001-12 Anti-CD9 mAb-ALP
MEX002-12 Anti-CD63 (LAMP-3) mAb-ALP
MEX003-12 Anti-CD81 (TAPA1) mAb-ALP
MEX-SA123 ExoCap™ Streptavidin CD9/CD63/CD81 Set
MEX123-60 Exosome CD9/CD63/CD81 mAb Set-Biotin
参考文献
  1. Spurr NK et al. Characterization and chromosomal assignment of a human cell surface antigen defined by the monoclonal antibody AUAI. Int J Cancer. 38, 631-6 (1986)(PMID: 3770992
  2. Koga Y et al. Improved recovery of exfoliated colonocytes from feces using newly developed immunomagnetic beads. Gastroenterol Res Pract. 2008, 605273 (2008)(PMID: 19125182
  3. Taylor DD, Gercel-Taylor C. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol. Oncol. 110, 13-21 (2008)(PMID: 18589210
  4. Marhaba R et al. CD44 and EpCAM: cancer-initiating cell markers. Curr Mol Med. 8, 784-804 (2008)(PMID: 19075676
  5. Rabinowits G et al. Exosomal microRNA: a diagnostic marker for lung cancer. Clin Lung Cancer 10, 42-46 (2009)(PMID: 19289371
  6. van der Gun BT et al. EpCAM in carcinogenesis: the good, the bad or the ugly. Carcinogenesis 31, 1913-21 (2010)(PMID: 20837599
製品
カテゴリー
分野
RNA-RNPネットワーク
がん
細胞膜表面抗原
エクソソーム
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※在庫につきましては2019年11月16日 00時05分時点における在庫数を表示してあります。
※価格の赤色表示につきましては、キャンペーン価格の表示となっております。
※このサイトからは直接注文はできません。ご注意ください。
※使用法の表記について:
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation,
FCM: Flow Cytometry NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation,
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
※使用法・交差性の表記について:
*: 論文で報告されております(MBLでは未確認)。詳しくはデータシートをご覧ください。
**: 導入元からの情報です(MBLでは評価中もしくは未確認)。
※保存温度の表記について: RT: 室温
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