Code No. | Product name | Synonyms | Reactivity | Applications | Function, localization |
---|---|---|---|---|---|
RN126PW | Anti-AHCY (SAHH) pAb |
adoHcyase |
Hu | WB/ IP | AHCY (SAHH) is the only enzyme that catalyzes the reversible hydrolysis of S-adenosylhomocysteine to adenosine and homocysteine. AHCY (SAHH) is involved in the regulation of intracellular methylation processes. |
RN122PW | Anti-ALKBH5 pAb | Hu/ Mo | WB/ IP | ALKBH5 is one of mammalian m6A demethylase, localized in nuclear speckles, catalyzes the direct removal of m6A modification on nuclear RNA and its demethylation affects RNA processing and RNA export. | |
RN125PW | Anti-HENMT1 pAb | HEN1, C1orf59 | Hu/ Mo/ Rat | WB | HENMT1, small RNA 2'-O-methyltransferase, mediates stabilization of piRNA by adding 2'-O-methyl group to the 3'-end of mammalian piRNAs. HENMT1 is preferentially expressed in testis and required for mouse spermatogenesis. |
RN127PW | Anti-NSUN2 (Human) pAb | MISU, MRT5, SAKI, TRM4 | Hu | WB/ IP | NSUN2, identified as tRNA m5C methyltransferase, catalyzes the conversion of cytidine to m5C in tRNAs, mRNA and miRNA. m5C RNA modifications by NSUN2 affects mRNA stability, translation regulation and miRNA biogenesis. |
RN124PW | Anti-RNMT (Human) pAb | KIAA0398, hCMT1c, MET, RG7MT1 | Hu | WB/ IP | RNMT, mRNA cap methyltransferase, is involved in cap formation at the 5'-end of nascent RNA via methylation of the 5'-cap. |
RN128PW | Anti-TRMT6 (Human) pAb | KIAA1153, TRM6 | Hu | WB/ IP | tRNA m1A58 methyltransferase (m1A58 MTase) catalyzes the conversion of A to m1A at position 58 in initiator methionyl-tRNA. Human m1A58 MTase consitis of a hetrotetramer formed by TRMT6 and TRMT61, an RNA-binding component and a catalytic component. |
RN123PW | Anti-YTHDF2 pAb | CAHL, HGRG8, NY-REN-2 | Hu/ Mo/ Rat(w)/ Ham | WB/ IP | YTHDF2, functioning as m6A reader protein, is involved in methylation-dependent RNA decay. Binding of YTHDF2 to m6A containing mRNAs leads to localization of the mRNAs to P-body and degradation. |