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HOME > Product search results > Code No. CY-8153 CircuLex Human PCSK9 Functional Assay Kit

Code No. CY-8153

CircuLex Human PCSK9 Functional Assay Kit

Availability (in Japan)

1-9

(In Japan at 17:00,
Apr 19, 2024 in JST)

Size

96 Assay

Data
  • Typical Standard Curve

    Typical Standard Curve

  • Binding activities of three types of recombinant PCSK9 proteins.

    Binding activities of three types of recombinant PCSK9 proteins.

Components Microplate, 10X Wash Buffer, Sample Dilution Buffer, PCSK9 Binding Activity Standard, Conjugate Dilution Buffer, 100X Biotinylated Detection Antibody, 100X HRP conjugated Streptavidin, Substrate Reagent, Stop Solution
Intended use This kit is primarily designed for the semi-quantitative in vitro measurement of functionally active of PCSK9 in serum which is capable of binding to LDL receptor (LDLR). This kit allows to measure active PCSK9 in a solid-phase assay
Storage temp. 4°C Manufacturer MBL
Sample serum, recombinant PCSK9
Measurement range 0.125 ~ 8 mAU/mL
Sensitivity 0.042 mAU/mL ~
Related products CY-8078 CircuLex Mouse/Rat PCSK9 ELISA Kit
CY-8079 CircuLex Human PCSK9 ELISA Kit
CY-8150 CircuLex PCSK9-LDLR in vitro Binding Assay Kit
CY-M1032 Anti-PCSK9 prodomain (Human) mAb
CY-M1033 Anti-PCSK9 (Human) mAb
CY-R2311 PCSK9 D374Y in culture medium
CY-R2330 PCSK9 Wild Type (Human)
CY-R2331 PCSK9 D374Y
CY-R2333 PCSK9 R194A
CY-R2340 LDLR EGF-AB domain
Citations

Function

  1. Ben Djoudi Ouadda A et al. Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor).Arterioscler Thromb Vasc Biol. 39, 1996-2013 (2019) (PMID:31553664)
Product category
Research area
Metabolism
Drug discovery
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