Code No. | W253-3 | |
Anti-Glypican 1 (Human) mAb | ||
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 00:05, Apr 20, 2024 in JST) |
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Clonality | Monoclonal | |
Clone | 12C1E2F | |
Isotype (Immunized Animal) |
Mouse IgG1κ | |
Applications | FCM 1-10 µg/mL |
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Immunogen (Antigen) |
Human Glypican 1 expressed Ba/F3transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening). | |
Reactivity [Gene ID] | Human[2817] |
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Storage buffer | PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | GPC1 | |
Background | Glypican 1 (GPC1) is a member of cell surface heparan sulfate proteoglycan family. GPC1 is a GPI-anchored type membrane protein and probably involves in the control of cell division and growth regulation. GPC1 also associates with fibrillar APP A-beta peptides in lipid rafts in Alzheimer disease brains. In pancreatic ductal adenocarcinoma, enhanced GPC1 expression is suggested to correlate with BMP and activin receptors. Down-regulation of GPC1 results in suppression of pancreatic cancer cell growth. | |
Related products | W164-3 Anti-RHBDD3 (Human) mAb M075-3 Mouse IgG1 (isotype control) MTG-001 Clear Back (Human Fc receptor blocking reagent) |
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Product category | Research area:Cancer Tools:Flow cytometry reagents |
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Data | ||
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