Antibody detailed product information
| Code No. | RN122PW | |
| Anti-ALKBH5 pAb | ||
| Size | 100 µL (1 mg/mL) | |
| Availability (in Japan) | 1-9
（In Japan at 17:00, Apr 19, 2024 in JST） |
|
| Clonality | Polyclonal | |
| Clone | Polyclonal | |
| Isotype (Immunized Animal) |
Rabbit Ig (aff.) | |
| Applications | WB 1:1,000 IP 5 µL/500 µL of cell extract from 5 x 106 cells/sample |
|
| Reactivity [Gene ID] | ||
| Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
| Storage temp. | -20°C | |
| Conjugate | Unlabeled | |
| Manufacturer | MBL | |
| Alternative names | ABH5, OFOXD, OFOXD1 | |
| Background | N(6)-methyladenosine (m6A) is one of the most abundant modified nucleosides found in some viral RNA and eukaryotic RNA including mRNA, tRNA, rRNA and lncRNA. It has been reported that m6A modification is involved in the regulation of mRNA export, stability and translation. alkB homolog 5, RNA demethylase (ALKBH5) and FTO are AlkB family proteins that function as mammalian m6A demethylases (‘erasers’). ALKBH5 catalyzes the direct removal of m6A modification on nuclear RNA and its demethylation affects RNA processing and RNA export. Whereas FTO is highly expressed in brain, ALKBH5 is highly expressed in testis and knockout of Alkbh5 gene in mice exhibits impaired male fertility. | |
| Related products | RN123PW Anti-YTHDF2 pAb RN1001 RIP-Assay Kit |
|
| Product category | Research area:RNA-RNP Network Brands:RiboCluster Profiler™ |
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| Data |   |
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- The availability is based on the information in Japan at 17:00, Apr 19, 2024 in JST.
- The special price is shown in red color.
- Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
- Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization - For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
- For storage temparature: RT: room temparature
- Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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