Code No. | PM066 | |
Anti-p62 C-terminal pAb | ||
Size | 100 µL | |
Availability (in Japan) | 10 or more
(In Japan at 17:33, Apr 26, 2024 in JST) |
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Clonality | Polyclonal | |
Clone | Polyclonal | |
Isotype (Immunized Animal) |
Guinea pig Ig (aff.) | |
Applications | WB 1:1,000 IP 5 µL/300 µL of cell extract from 3x106 cells IC 1:500 IH 1:100 |
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Immunogen (Antigen) |
Human p62 C-terminal peptide | |
Reactivity [Gene ID] | ||
Storage buffer | PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | SQSTM1, sequestosome 1, p62 | |
Background | p62/SQSTM1 interacts with various molecular groups such as RIP, TRAF6, ERK, aPKCs, and poly-ubiquitin through PB1 domain, Zn finger domain, and UBA domain. This protein directly interacts with LC3, which is localized on autophagosome membrane, and is degradated by autophagic-lysosome pathway. p62 regulates ubiquitin-positive protein aggregates caused by autophagy deficiency. | |
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Product category | Research area:Autophagy | |
Data | ||
Citations | Western Blotting
Immunocytochemistry
Immunohistochemistry
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