Code No. | CM005-3 | |
Anti-SynCAM (TSLC1/CADM1) (Human) mAb | ||
It is reported that clone 9D2 can be used in adhesion blocking experiments in the references. | ||
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 17:33, Apr 26, 2024 in JST) |
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Clonality | Monoclonal | |
Clone | 9D2 | |
Isotype (Immunized Animal) |
Chicken IgY | |
Applications | FCM 1 µg/mL (final concentration) |
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Immunogen (Antigen) |
Recombinant SynCAM/Fc fusion protein | |
Reactivity [Gene ID] | Human[23705] |
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Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | cell adhesion molecule 1, BL2, IGSF4, IGSF4A, NECL2, Necl-2, RA175, ST17, sTSLC-1, sgIGSF | |
Background | SynCAM (Synaptic Cell Adhesion Molecule), also known as TSLC1 (tumor suppressor in lung cancer-1), SgIGSF, or CADM1, is a homophilic, transmembrane Ig-domain containing protein with intracellular PDZ protein-binding motifs. Although originally identified as a tumor suppressor of small lung cell carcinomas, SynCAM appears to be primarily involved in intracellular adhesion and synapse formation. The majority of SynCAM is localized to synaptic sites where it initiates synaptic assembly and synapse differentiation throughout the central nervous system. SynCAM also mediates the cellular adhesion of spermatogenic cells to Sertoli cells and mast cells to fibroblasts. | |
Related products | PM084 Normal Chicken IgY PM084-4 Normal Chicken IgY-FITC PM084-5 Normal Chicken IgY-PE CM004-3 Anti-SynCAM (TSLC1/CADM1) mAb CM004-4 Anti-SynCAM (TSLC1/CADM1) mAb-FITC CM004-5 Anti-SynCAM (TSLC1/CADM1) mAb-PE CM004-6 Anti-SynCAM (TSLC1/CADM1) mAb-Biotin CM004-A64 Anti-SynCAM (TSLC1/CADM1) mAb-Alexa Fluor™ 647 |
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Product category | Research area:Neuroscience | |
Data | ||
References |
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