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HOME > Product search results > Code No. D365-3 Anti-PIWIL2 (MILI) (Mouse) mAb

Code No. D365-3

Anti-PIWIL2 (MILI) (Mouse) mAb

Availability (in Japan)

10 or more

(In Japan at 01:30,
Sep 23, 2017 in JST)

Size

100 µg/100 µL

Data
  • Western Blotting

  • Immunoprecipitation

  • Immunohistochemistry

Clonality Monoclonal Clone 3G5-E6
Isotype (Immunized Animal) Mouse IgG2aκ
Applications
WB
1 µg/mL  
IP
2 μg/sample  
IH
1 µg/mL (Heat treatment is necessary for paraffin embedded sections.)  
Reactivity [Gene ID]

Human(-), Mouse[57746]

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names Piwi-like protein 2
Background PIWIL2 (MILI) is one of three murine PIWI subfamily proteins. They are expressed specifically in gonads, which then form complexes with small RNAs termed piRNAs; and these are responsible for transposon silencing in a mechanism known as “RNA silencing”.
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References
  1. Kuramochi-Miyagawa S et al. Two mouse piwi-related genes: miwi and mili. Mech Dev. 108, 121-33 (2001)(PMID: 11578866
  2. Kuramochi-Miyagawa S et al. Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development 131, 839-49 (2004)(PMID: 14736746
  3. Aravin A et al. A novel class of small RNAs bind to MILI protein in mouse testes. Nature 442, 203-7 (2006)(PMID: 16751777
  4. Aravin A et al. Developmentally regulated piRNA clusters implicate MILI in transposon control. Science 316, 744-7 (2007)(PMID: 17446352
  5. Manakov SA et al. MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation. Cell Rep. 12, 1234-43 (2015)(PMID: 26279574
Product category
Research area
Stem cell research
RNA-RNP Network
Epigenetics
Cancer
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 01:30, Sep 23, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.