Availability (in Japan)
10 or more
(In Japan at 17:00,
Mar 29, 2024 in JST)
Size
100 µL (1 mg/mL)
Data | |||||
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Clonality | Monoclonal | Clone | AK9 | ||
Isotype (Immunized Animal) | Mouse IgG1 | ||||
Applications |
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Immunogen (Antigen) | hybridoma was established by fusion of splenocytes from PV model mouse and P3 mouse myeloma cells | ||||
Reactivity [Gene ID] | Human(-), Mouse[13512] |
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Storage buffer | 1 mg/mL in PBS, pH 7.2 | ||||
Storage temp. | 4°C | Conjugate | Unlabeled | Manufacturer | MBL |
Alternative names | Dsg3 | ||||
Background | Pemphigus vulgaris (PV) is a life -threatening autoimmune blistering disease of the skin and mucous membranes. In patients of PV, IgG autoantibodies against the cell surface of keratinocytes in stratified squamous epithelia play a major pathogenic role in loss of cell-cell adhesion. The autoimmune target of PV is desmoglein 3 (Dsg3), which is a member of the cadherin family of calcium-depending, transmembrane glycoprotein. | ||||
Related products | D218-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide) D219-3 Anti-Desmoglein 3 (Mouse) mAb (No Azide) M075-3 Mouse IgG1 (isotype control) |
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Citations |
Immunoprecipitation
Immunohistochemistry
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Product category |
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