This site is for customers in Asia. Customers in China & other regions, please go to Global page.
HOME > Product search results > Code No. W077-3 Anti-GRK5 (Human) mAb

Code No. W077-3

Anti-GRK5 (Human) mAb

Availability (in Japan)

10 or more

(In Japan at 01:30,
May 24, 2017 in JST)

Size

100 µg/100 µL

Data
  • Flow Cytometry

Clonality Monoclonal Clone 2F11C3
Isotype (Immunized Animal) Mouse IgG2aκ
Applications
FCM
1-10 µg/mL  
Immunogen (Antigen) Human GRK5 expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Reactivity [Gene ID]

Human[2869]

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names G protein-coupled receptor kinase 5, GPRK5
Background G protein-coupled receptor kinase 5 (GRK5) is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. GRK5 is expressed ubiquitously in human tissues including the heart, placenta, lung, skeletal muscle, brain, liver, pancreas, and kidney. GRK5 phosphorylates the activated forms of G protein-coupled receptors, facilitates receptor desensitization and internalization, and leads to receptor downregulation. High expression levels of GRK5 are observed in an aggressive prostate cancer PC3 cell line.
Related products CY-SPG03 GRK5 (Human), Active
M076-3 Mouse IgG2a (isotype control)
MTG-001 Clear Back (Human Fc receptor blocking reagent)
W147-3 Anti-TYRO3 (Human) mAb
W164-3 Anti-RHBDD3 (Human) mAb
References
  1. Kojima T, Kitamura T. A signal sequence trap based on a constitutively active cytokine receptor. Nat. Biotechnol. 17, 487-490 (1999)(PMID: 10331810
Product category
Research area
Cancer
Signal transduction
Tools
Flow cytometry reagents
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 01:30, May 24, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.