This site is for customers in Asia. Customers in China & other regions, please go to Global page.
HOME > Product search results > Code No. W029-3 Anti-IGFBP1 (Human) mAb

Code No. W029-3

Anti-IGFBP1 (Human) mAb

Availability (in Japan)

10 or more

(In Japan at 01:30,
May 24, 2017 in JST)

Size

100 µL: 1 mg/mL

Data
  • Flow Cytometry

Clonality Monoclonal Clone 2B9-2
Isotype (Immunized Animal) Mouse IgG2bκ
Applications
FCM
1-10 µg/mL  
Immunogen (Antigen) Human IGFBP1 expressed Ba/F3transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Reactivity [Gene ID]

Human[3438]

Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names AFBP, IBP1, PP12, IGF-BP25, hIGFBP-1
Background IGFBP1, also known as placental protein 12 (PP12), is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin domain. IGFBP1 circulates in the plasma and has been shown to either inhibit or stimulate the growth promoting effects of its ligands called insulin-like growth factors (IGFs) I and II. High expression levels of IGFBP1 have been implicated in metastasis of prostate cancer.
Related products M076-3 Mouse IgG2a (isotype control)
MTG-001 Clear Back (Human Fc receptor blocking reagent)
W031-3 Anti-IGFBP6 (Human) mAb
W147-3 Anti-TYRO3 (Human) mAb
W164-3 Anti-RHBDD3 (Human) mAb
References
  1. Kojima T, Kitamura T. A signal sequence trap based on a constitutively active cytokine receptor. Nat Biotechnol. 17, 487-90 (1999)(PMID: 10331810
  2. Dolcini L et al. Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms. . 276, 6033-46 (2009)(PMID: 197650
  3. Sala A et al. Structure and properties of the C-terminal domain of insulin-like growth factor-binding protein-1 isolated from human amniotic fluid. J Biol Chem. 280, 29812-9 (2005)(PMID: 15972819
  4. Jones JI et al. Identification of the sites of phosphorylation in insulin-like growth factor binding protein-1. Regulation of its affinity by phosphorylation of serine 101. J Biol Chem.  268, 1125-31 (1993)(PMID: 7678248
Product category
Research area
Cancer
Tools
Flow cytometry reagents
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 01:30, May 24, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.