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HOME > Product search results > Code No. PM096 Anti-PER2 (Human) pAb

Code No. PM096

Anti-PER2 (Human) pAb

Availability (in Japan)

10 or more

(In Japan at 01:30,
May 25, 2017 in JST)

Size

50 µL

Data
  • Western Blotting

  • Immunoprecipitation

Clonality Polyclonal Clone Polyclonal
Isotype (Immunized Animal) Guinea pig Ig (aff.)
Applications
WB
1:500  
IP
2 µL/sample  
Reactivity [Gene ID]

Human[8864], Mouse(-)[18627]

Storage buffer TBS/50% glycerol, pH 7.5
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names period circadian clock 2, FASPS, FASPS1, period2
Background The circadian clock is a 24-hour endogenous oscillator, which cycles via transcriptional/translational feedback loops of clock genes and their products in individual cells. CLOCK and BMAL1 are positive factors in the loop, and their complex binds to E-box elements of Period (PER) and Cryptochrome (CRY) genes. In turn, this E-box-dependent transactivation is suppressed by binding of PER and CRY proteins to the CLOCK-BMAL1 complex. Gene polymorphisms of PER2 are also associated with improper cell division, cancer development, improper alcohol intake, and familial advanced sleep-phase syndrome (FASPS).
Related products D335-3 Anti-BMAL1 (Mouse) mAb
D334-3 Anti-CLOCK (Mouse) mAb
D333-3 Anti-CLOCK (Mouse) mAb
PM075 Anti-GNAT2 (Zebrafish) pAb
PM079 Anti-DBP (Mouse) pAb
D349-3 Anti-CLOCK (Mouse) mAb
PM081 Anti-Cry1 (Mouse) pAb
PM082 Anti-Cry2 (Mouse) pAb
PM083 Anti-Per2 (Mouse) pAb
PM087 Anti-Chrono (Mouse) pAb
PM091 Anti-Per1 (Mouse) pAb
PM092 Anti-NR1D1 (Rev-erbα) pAb
PM093 Anti-NR1D2 (Rev-erbβ) pAb
PM097 Anti-NFIL3 (E4BP4) pAb
M225-3 Anti-NFIL3 (E4BP4) chimeric mAb
PM067 Normal Guinea Pig IgG
CY-P1016 Anti-SIRT1 pAb
CY-1173 CycLex® CaM-kinase II Assay Kit
CY-E1151 NAD+-Dependent Deacetylase SIRT1(recombinant)
CY-E1152 NAD+-Dependent Deacetylase SIRT2(recombinant)
D361-3 Anti-BMAL1 mAb
References
  1. Zheng B et al. Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock. Cell 105, 683-94 (2001)(PMID: 11389837
  2. Bae K et al. Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock. Neuron 30, 525-36 (2001)(PMID: 11395012
  3. Lee Y et al. Stoichiometric relationship among clock proteins determines robustness of circadian rhythms. J Biol Chem. 286, 7033-42 (2011)(PMID: 21199878
  4. Siepka SM et al. Genetics and Neurobiology of Circadian Clocks in Mammals. Cold Spring Harb Symp Quant Biol 72, 251-259 (2007)(PMID: 18419282
  5. Ko CH, Takahashi JS. Molecular components of the mammalian circadian clock. Hum. Mol. Genet. 15, R271-7 (2006)(PMID: 16987893
  6. Camacho F et al. Human casein kinase Idelta phosphorylation of human circadian clock proteins period 1 and 2. FEBS Lett. 489, 159–165 (2001)(PMID: 11165242
Product category
Research area
Circadian rhythm
Signal transduction
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 01:30, May 25, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.