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HOME > Product search results > Code No. PM075 Anti-GNAT2 (Zebrafish) pAb

Code No. PM075

Anti-GNAT2 (Zebrafish) pAb

Availability (in Japan)

10 or more

(In Japan at 01:30,
Jun 24, 2017 in JST)

Size

100 µL

Data
  • Western Blotting

  • Immunofluorescence

Clonality Polyclonal Clone Polyclonal
Isotype (Immunized Animal) Rabbit Ig (aff.)
Applications
WB
1:1,000-2,000  
IF
1:800 (frozen section)  
Immunogen (Antigen) KLH conjugated synthetic peptide, MDRICKPDYLPT (corresponding to amino acid residues 159-170 of zebrafish gnat2)
Reactivity [Gene ID]

Zebrafish[140429]

Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names cone transducin alpha subunit,Guanine nucleotide bindinf protein(G protein),alpha transducing activity polypeptide2
Background Transducin, also known as Gt, is a heterotrimeric guanine nucleotide-binding protein with three polypeptide chains: alpha, beta, and gamma. Gt is expressed in rods and cones of retinal photpreceptors.Transducin alpha-subunits are different in rods and cones, being encoded by different genes, GNAT1 in rods and GNAT2 in cones respectively. GNAT2 plays an important role in the light-signalling pathway in the retinal cone cells and also associates with synchronization of circadian rhythm in vertebrates including Zebrafish and Xenopus, as well as mouse and human.
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Citations

Immunofluorescence

  1. Ogawa Y et al. Homeobox transcription factor Six7 governs expression of green opsin genes in zebrafish. Proc Biol Sci. 282 pii: 20150659 (2015)(PMID:26180064)
References
  1. Brockerhoff SE et al. Light stimulates a transducin-independent increase of cytoplasmic Ca2+ and suppression of current in cones from the zebrafish mutant nof. J Neurosci. 23, 470-80 (2003)
Product category
Research area
Neuroscience
Circadian rhythm
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 01:30, Jun 24, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.